taste receptor, type 1, member 2 (Tas1r2, TS1R2) (1st Extracellular Domain) antibody

Antigen: taste receptor, type 1, member 2 (Tas1r2, TS1R2)

Binding Site: 1st Extracellular Domain

Clonality: Polyclonal

Host: Rabbit

Reactivity: Mouse (Murine)

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Catalog no.: ABIN350957

Additional Information

UniProt: Q925I4

Immunogen: A synthetic peptide from 1t extracellular domain of mouse taste receptor, type 1, member 2 (Tas1r2, TS1R2) conjugated to an immunogenic carrier protein was used as the immunogen.

Format: Lyophilized

Description: FUNCTION: Putative taste receptor. TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners. SUBUNIT: Forms heterodimers with TAS1R3. SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. TISSUE SPECIFICITY: Expressed mainly in circumvallate and foliate taste papillae.<||a href="http://www.enzim.hu/hmmtop1.1/server/submit.html"><||/a> Also known as: Taste receptor type 1 member 2, sweet taste receptor T1R2, G-protein coupled receptor 71, Tas1r2, Gpr71, T1r2, Tr2, TS1R2.

Specificity: Appears to be specific for TAS1R2.

Application Details

Application Notes: IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Purity: whole serum

Storage: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Restrictions: For Research Use only

Publications

Montmayeur, Liberles, Matsunami et al.: "A candidate taste receptor gene near a sweet taste locus." in: Nature neuroscience, Vol. 4, Issue 5, pp. 492-8, 2001 (PubMed).

Nelson, Hoon, Chandrashekar et al.: "Mammalian sweet taste receptors." in: Cell, Vol. 106, Issue 3, pp. 381-90, 2001 (PubMed).

Ariyasu, Matsumoto, Kyono et al.: "Taste receptor T1R3 is an essential molecule for the cellular recognition of the disaccharide trehalose." in: In vitro cellular & developmental biology. Animal, Vol. 39, Issue 1-2, pp. 80-8, 2003 (PubMed).