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Details for Product No. ABIN350971

Taste Receptor, Type 2, Member 16 (TAS2R16) (Cytoplasmic Domain) antibody

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Antigen
Synonyms T2R16, T2R3, Tas2r16, Gm465, T2R18, Tas2r18, mGR18, mt2r40
Epitope
»Alternatives Cytoplasmic Domain
Reactivity
»Alternatives Rat (Rattus)
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 5 references available
Catalog no. ABIN350971
Quantity 100 µL
Price
454.67 $   Plus shipping costs $45.00
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Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide from a cytoplasmic domain of rat taste receptor, type 2, member 16 (TAS2R16, T2R16) conjugated to an immunogenic carrier protein was used as the immunogen.
Specificity Appears to be specific for TAS2R16.
Purity whole serum
Alternative Name taste receptor, type 2, member 16 (TAS2R16, T2R16)
Background Function: Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5.
Tissue specificity: Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells. Expressed in the antrum and fundus (part of the stomach), duodenum and in gastric endocrine cells.
Subcellular location: Cell membrane, Multi-pass membrane protein. Also known as: T2R16, T2R18, T2R3, Tas2r18, Tas2r3, Tas2r16, T2R16.
UniProt Q9JKU0
Application Notes IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Storage -20 °C
Adler, Hoon, Mueller et al.: "A novel family of mammalian taste receptors." in: Cell, Vol. 100, Issue 6, pp. 693-702, 2000 (PubMed).

Chandrashekar, Mueller, Hoon et al.: "T2Rs function as bitter taste receptors." in: Cell, Vol. 100, Issue 6, pp. 703-11, 2000 (PubMed).

Wu, Rozengurt, Yang et al.: "Expression of bitter taste receptors of the T2R family in the gastrointestinal tract and enteroendocrine STC-1 cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 4, pp. 2392-7, 2002 (PubMed).

Montmayeur, Matsunami: "Receptors for bitter and sweet taste." in: Current opinion in neurobiology, Vol. 12, Issue 4, pp. 366-71, 2002 (PubMed).

Zhang, Hoon, Chandrashekar et al.: "Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways." in: Cell, Vol. 112, Issue 3, pp. 293-301, 2003 (PubMed).

Alternatives for antigen "Taste Receptor, Type 2, Member 16 (TAS2R16)", type "Antibodies"
Hosts (22)
Reactivities (21), (1)
Applications (13), (10), (8), (4), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (2), (1)
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