Search, Find and Buy Antibodies, ELISA Kits and Proteins.
Loading Loading
Order hotline:
phone +1 404 474 4654
fax +1 888 205 9894 (TF)
Details for Product No. ABIN350974

Taste Receptor, Type 2, Member 4 (Tas2r108) (Cytoplasmic Domain) antibody

Request
Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms T2R4, T2R16, Tas2r4, T2R108, T2r8, Tas2r8, mGR08, mt2r8, T2R1, tas2r4, tas2r1l
Epitope
»Alternatives Cytoplasmic Domain
Reactivity
»Alternatives Mouse (Murine)
Host
»Alternatives Rabbit
Clonality Polyclonal
Application
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 5 references available
Catalog no. ABIN350974
Quantity 100 µL
Price
454.67 $   Plus shipping costs $45.00
Shipping to
Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide from a cytoplasmic domain of mouse taste receptor, type 2, member 4 (Tas2r4, T2R4) conjugated to an immunogenic carrier protein was used as the immunogen.
Specificity Appears to be specific for TAS2R4.
Purity whole serum
Alternative Name taste receptor, type 2, member 4 (Tas2r4, T2R4)
Background Function: Gustducin-coupled receptor for denatonium and N(6)-propyl-2-thiouracil implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5.
Subunit: Forms heterodimers with TAS1R3.
Subcellular location: Cell membrane, Multi-pass membrane protein.
Tissue specificity: Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells. Expressed in 15% taste bud cells in circumvallate and foliate papillae but only in 2% in fungiform papillae. Also known as: Tas2r4, Tas2r108, Tas2r8, T2R4, Taste receptor type 2 member 8, TA2R4.
UniProt Q9JKT3
Application Notes IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Storage -20 °C
Adler, Hoon, Mueller et al.: "A novel family of mammalian taste receptors." in: Cell, Vol. 100, Issue 6, pp. 693-702, 2000 (PubMed).

Chandrashekar, Mueller, Hoon et al.: "T2Rs function as bitter taste receptors." in: Cell, Vol. 100, Issue 6, pp. 703-11, 2000 (PubMed).

Zhang, Hoon, Chandrashekar et al.: "Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways." in: Cell, Vol. 112, Issue 3, pp. 293-301, 2003 (PubMed).

Nelson, Munger, Boughter: "Taste sensitivities to PROP and PTC vary independently in mice." in: Chemical senses, Vol. 28, Issue 8, pp. 695-704, 2003 (PubMed).

Wu, Chen, Rozengurt: "Genomic organization, expression, and function of bitter taste receptors (T2R) in mouse and rat." in: Physiological genomics, Vol. 22, Issue 2, pp. 139-49, 2005 (PubMed).

Alternatives for antigen "Taste Receptor, Type 2, Member 4 (Tas2r108)", type "Antibodies"
Hosts (5), (1)
Reactivities (5), (1)
Applications (5), (3), (1), (1), (1), (1), (1), (1)
Epitopes (1), (1)
Beacon