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Details for Product No. ABIN350980

Taste Receptor, Type 2, Member 42 (TAS2R42) antibody

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Antigen
Synonyms T2R24, T2R55, TAS2R55, hT2R55, T2R67
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Application
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 3 references available
Catalog no. ABIN350980
Quantity 100 µL
Price
454.67 $   Plus shipping costs $45.00
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Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide from human taste receptor, type 2, member 42 (TAS2R42, T2R42, T2R55, hT2R55, T2R24) conjugated to an immunogenic carrier protein was used as the immunogen.
Specificity Appears to be specific for TAS2R42.
Purity whole serum
Alternative Name taste receptor, type 2, member 42 (TAS2R42, T2R42, T2R55, hT2R55, T2R24)
Background Function: Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5.
Subcellular location: Membrane, Multi-pass membrane protein.
Miscellaneous: Most taste cells may be activated by a limited number of bitter compounds, individual taste cells can discriminate among bitter stimuli. Also known as: Taste receptor type 2 member 42, T2R42, T2R55, TAS2R42, TAS2R55, hT2R55, T2R24.
UniProt Q7RTR8
Application Notes IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Storage -20 °C
Shi, Zhang, Yang et al.: "Adaptive diversification of bitter taste receptor genes in Mammalian evolution." in: Molecular biology and evolution, Vol. 20, Issue 5, pp. 805-14, 2003 (PubMed).

Fischer, Gilad, Man et al.: "Evolution of bitter taste receptors in humans and apes." in: Molecular biology and evolution, Vol. 22, Issue 3, pp. 432-6, 2005 (PubMed).

Scherer, Muzny, Buhay et al.: "The finished DNA sequence of human chromosome 12." in: Nature, Vol. 440, Issue 7082, pp. 346-51, 2006 (PubMed).

Alternatives for antigen "Taste Receptor, Type 2, Member 42 (TAS2R42)", type "Antibodies"
Hosts (1)
Reactivities (1)
Applications (1), (1)
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