Type 2 Taste Receptor Member 47 (TAS2R30) antibody

Details for Product No. ABIN350988
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Antigen
Synonyms T2R30, T2R47, TAS2R47
Reactivity
Human, Rat (Rattus), Mouse (Murine)
(2)
Host
Rabbit
(1), (1)
Clonality
Polyclonal
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(2), (1), (1)
Pubmed 4 references available
Catalog no. ABIN350988
Quantity 100 µL
Price
454.67 $   Plus shipping costs $45.00
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Immunogen A synthetic peptide as a part of human taste receptor, type 2, member 47 (TAS2R47, T2R47) conjugated to immunogenic carrier protein was used as the immunogen. The antibody generated using this antigen is expected to also recognise TAS2R43, TAS2R44, TAS2R4
Specificity Specific for GRID2.
Purification whole serum
Alternative Name taste receptor, type 2, member 47 (TAS2R47, T2R47)
Background Function: Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5.
Subcellular location: Membrane, Multi-pass membrane protein.
Tissue specificity: Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells.
Miscellaneous: Most taste cells may be activated by a limited number of bitter compounds, individual taste cells can discriminate among bitter stimuli. Also known as: Taste receptor type 2 member 47,TAS2R47.
UniProt Q61625
Research Area Neurology, Amino Acids
Application Notes A dilution of 1 : 300 to 1 : 4000 is recommended.
The optimal dilution should be determined by the end user.
Restrictions For Research Use only
Format Liquid
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage -20 °C
Storage Comment Maintain the reconstituted antibodies frozen at -20 °C for long term storage and refrigerated at 2-8 °C for a shorter term.
Expiry Date 12 months
General Montmayeur, Matsunami: "Receptors for bitter and sweet taste." in: Current opinion in neurobiology, Vol. 12, Issue 4, pp. 366-71, 2002 (PubMed).

Bufe, Hofmann, Krautwurst et al.: "The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides." in: Nature genetics, Vol. 32, Issue 3, pp. 397-401, 2002 (PubMed).

Zhang, Hoon, Chandrashekar et al.: "Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways." in: Cell, Vol. 112, Issue 3, pp. 293-301, 2003 (PubMed).

Fischer, Gilad, Man et al.: "Evolution of bitter taste receptors in humans and apes." in: Molecular biology and evolution, Vol. 22, Issue 3, pp. 432-6, 2005 (PubMed).

Hosts (1), (1)
Reactivities (2)
Applications (2), (1), (1)
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