Two Pore Segment Channel 1 (TPCN1) (C-Term) antibody

Antigen: Two Pore Segment Channel 1 (TPCN1)

Synonyms: TPC1, FLJ20612, KIAA1169, Tpc1, mKIAA1169, 5730403B01Rik

Binding Site: C-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Catalog no.: ABIN351014

Additional Information

Alternative name: TPC1 (Two pore calcium channel protein 1)

UniProt: Q9ULQ1

Immunogen: A synthetic peptide from the c-terminal region of human TPC1 (Two pore calcium channel protein 1) conjugated to an immunogenic carrier protein was used as the immunogen.

Format: Lyophilized

Description: Function: May function as one of the major voltage-gated Ca2+ channel (VDCC) across the plasma membrane. Subcellular location: Membrane; Multi-pass membrane protein. Tissue specificity: Highest expression found in the heart and kidney, and lowest expression found in the spleen. Also known as: Two pore calcium channel protein 1, Voltage-dependent calcium channel protein TPC1, TPCN1.

Specificity: Appears to be specific for TPC1.

Application Details

Application Notes: IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not tested in other applications.

Purity: whole serum

Storage: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Restrictions: For Research Use only

Publications

Hirosawa, Nagase, Ishikawa et al.: "Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain." in: DNA research : an international journal for rapid publication of reports on genes and genomes, Vol. 6, Issue 5, pp. 329-36, 2000 (PubMed).

Nakajima, Okazaki, Yamakawa et al.: "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones." in: DNA research : an international journal for rapid publication of reports on genes and genomes, Vol. 9, Issue 3, pp. 99-106, 2002 (PubMed).

Ota, Suzuki, Nishikawa et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003 (PubMed).