Two Pore Calcium Channel 2 (TPCN2) (cytoplasmic domain) antibody

Antigen: Two Pore Calcium Channel 2 (TPCN2)

Synonyms: TPC2, SHEP10, FLJ41094, BC025890, MGC32411, D830047E22Rik, tpcn2

Epitope: cytoplasmic domain

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Catalog no.: ABIN351017

Additional Information

Alternative name: TPC2 (Two pore calcium channel protein 2) (cytoplasmic domain)

Swiss-Prot: Q8NHX9

Immunogen: A synthetic peptide from an extracellular domain of human TPC2 (Two pore calcium channel protein 2) conjugated to an immunogenic carrier protein was used as the immunogen.

Format: Lyophilized

Description: Function: May function as one of the major voltage-gated Ca2+ channel (VDCC) across the plasma membrane. Subcellular location: Membrane; Multi-pass membrane protein. Also known as: Two pore calcium channel protein 2, Voltage-dependent calcium channel protein TPC2, TPCN2.

Specificity: Appears to be specific for TPC2.

Application Details

Application Notes: IHC, WB (confirmed by recombinant protein). A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not tested in other applications.

Purity: whole serum

Storage: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Restrictions: For Research Use only

Publications

Publications: Taylor, Noguchi, Totoki et al.: "Human chromosome 11 DNA sequence and analysis including novel gene identification." in: Nature, Vol. 440, Issue 7083, pp. 497-500, 2006 (PubMed).

Sulem, Gudbjartsson, Stacey et al.: "Two newly identified genetic determinants of pigmentation in Europeans." in: Nature genetics, Vol. 40, Issue 7, pp. 835-7, 2008 (PubMed).