Trafficking Protein Particle Complex 1 (TRAPPC1) (internal) antibody

Antigen: Trafficking Protein Particle Complex 1 (TRAPPC1)

Synonyms: BET5, MUM2, D11Ertd172e, zgc:100969, MGC83988, bet5, mum2

Epitope: internal

Clonality: Polyclonal

Host: Rabbit

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Catalog no.: ABIN351029

Additional Information

Alternative name: Trafficking protein particle complex subunit 1 (TRAPPC1, TPPC1, MUM-2, BET5) (internal part)

Swiss-Prot: Q9Y5R8

Immunogen: A synthetic peptide from the internal part of human internal part of Trafficking protein particle complex subunit 1 (TRAPPC1, TPPC1, MUM-2, BET5) conjugated to an immunogenic carrier protein was used as the immunogen. The immunogen is homologous with the corresponding sequence in mouse, rat and chicken.

Format: Lyophilized

Description: FUNCTION: May play a role in vesicular transport from endoplasmic reticulum to Golgi. SUBUNIT: Part of the multisubunit TRAPP (transport protein particle) complex. SUBCELLULAR LOCATION: Golgi apparatus, cis-Golgi network. Endoplasmic reticulum. Also known as: Multiple myeloma protein 2, MUM-2, TRAPPC1, BET5, MUM2.

Specificity: Appears to be specific for TPPC1.

Application Details

Application Notes: IHC, WB. A dilution of 1 : 300 to 1 : 4000 is recommended. The optimal dilution should be determined by the end user.

Purity: whole serum

Storage: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Restrictions: For Research Use only

Images

IHC on rat spinal cord using Rabbit antibody to internal part of Trafficking protein particle complex subunit 1 (TRAPPC1, TPPC1, MUM-2, BET5): whole serum (ABIN351029) at 1 : 2000 dilution. Pre-absorption of the antibody with the immunising peptide completely abolishes the immunostaining (not shown).

IHC on rat spinal cord using Rabbit antibody to internal part of Trafficking protein particle complex subunit 1 (TRAPPC1, TPPC1, MUM-2, BET5): whole serum (ABIN351029) at 1 : 2000 dilution. Pre-absorption of the antibody with the immunising peptide completely abolishes the immunostaining (not shown).

IHC on rat spinal cord using Rabbit antibody to internal part of Trafficking protein particle complex subunit 1 (TRAPPC1, TPPC1, MUM-2, BET5): whole serum (ABIN351029) at 1 : 2000 dilution. Pre-absorption of the antibody with the immunising peptide completely abolishes the immunostaining (not shown).

Publications

Publications: Chiari, Foury, De Plaen et al.: "Two antigens recognized by autologous cytolytic T lymphocytes on a melanoma result from a single point mutation in an essential housekeeping gene." in: Cancer research, Vol. 59, Issue 22, pp. 5785-92, 1999 (PubMed).

Gavin, Boesche, Krause et al.: "Functional organization of the yeast proteome by systematic analysis of protein complexes." in: Nature, Vol. 415, Issue 6868, pp. 141-7, 2002 (PubMed).