Trafficking protein particle complex subunit 3 (TRAPPC3, TPPC3, BET3) (N-Term) antibody

Antigen: Trafficking protein particle complex subunit 3 (TRAPPC3, TPPC3, BET3)

Binding Site: N-Term

Clonality: Polyclonal

Host: Rabbit

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Catalog no.: ABIN351032

Additional Information

UniProt: O43617

Immunogen: A synthetic peptide from the n-terminal of human Trafficking protein particle complex subunit 3 (TRAPPC3, TPPC3, BET3) conjugated to an immunogenic carrier protein was used as the immunogen. The immunogen is homologous in mouse, rat and chicken.

Format: Lyophilized

Isotype: IgG

Description: FUNCTION: May play a role in vesicular transport from endoplasmic reticulum to Golgi. SUBUNIT: Homodimer. Heterodimer with TRAPPC6A. Part of the multisubunit TRAPP (transport protein particle) complex. SUBCELLULAR LOCATION: Golgi apparatus, cis-Golgi network. Endoplasmic reticulum. Also known as: Trafficking protein particle complex subunit 3, TRAPPC3, TPPC3.

Specificity: Appears to be specific for TPPC3.

Application Details

Application Notes: IHC, WB. A concentration of 10-50 µg/ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.

Purity: IgG

Storage: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Restrictions: For Research Use only

Publications

Sacher, Jiang, Barrowman et al.: "TRAPP, a highly conserved novel complex on the cis-Golgi that mediates vesicle docking and fusion." in: The EMBO journal, Vol. 17, Issue 9, pp. 2494-503, 1998 (PubMed).

Gavin, Bösche, Krause et al.: "Functional organization of the yeast proteome by systematic analysis of protein complexes." in: Nature, Vol. 415, Issue 6868, pp. 141-7, 2002 (PubMed).

Kim, Yi, Lee et al.: "Biochemical and crystallographic studies reveal a specific interaction between TRAPP subunits Trs33p and Bet3p." in: Traffic (Copenhagen, Denmark), Vol. 6, Issue 12, pp. 1183-95, 2005 (PubMed).