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Details for Product No. ABIN351045

Transmembrane Channel-Like 2 (Tmc2) (1st Cytoplasmic Loop) antibody

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Antigen
Synonyms C20orf145, dJ686C3.3, CWEA2
Epitope
»Alternatives 1st Cytoplasmic Loop
Reactivity
»Alternatives Mouse (Murine)
Host
»Alternatives Rabbit
Clonality Polyclonal
Application
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 3 references available
Catalog no. ABIN351045
Quantity 100 µL
Price
454.67 $   Plus shipping costs $45.00
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Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide from the 1t cytoplasmic loop of mouse transmembrane channel-like protein 2 (TMC2) conjugated to an immunogenic carrier protein was used as the immunogen.
Specificity Appears to be specific for TMC2.
Purity whole serum
Alternative Name transmembrane channel-like protein 2 (TMC2)
Background Function: May be required for the normal function of cochlear hair cells.
Subcellular location: Membrane, Multi-pass membrane protein.
Tissue specificity: Inner ear and testis.
Developmental stage: Expressed at low, constant levels in temporal bone from embryonic day 14 to day 1 after birth. Increases by 8 to 16-fold at day 5, 10 and 20. Also known as: TMC2,transmembrane cochlear-expressed protein 2, 4933416G09Rik.
UniProt Q8R4P4
Application Notes IHC, WB. A dilution of 1 : 400 to 1 : 5000 is recommended. The optimal dilution should be determined by the end user.
Restrictions For Research Use only
Format Lyophilized
Storage -20 °C
Keresztes, Mutai, Heller: "TMC and EVER genes belong to a larger novel family, the TMC gene family encoding transmembrane proteins." in: BMC genomics, Vol. 4, Issue 1, pp. 24, 2003 (PubMed).

Kurima, Yang, Sorber et al.: "Characterization of the transmembrane channel-like (TMC) gene family: functional clues from hearing loss and epidermodysplasia verruciformis." in: Genomics, Vol. 82, Issue 3, pp. 300-8, 2003 (PubMed).

Carninci, Kasukawa, Katayama et al.: "The transcriptional landscape of the mammalian genome." in: Science (New York, N.Y.), Vol. 309, Issue 5740, pp. 1559-63, 2005 (PubMed).

Alternatives for antigen "Transmembrane Channel-Like 2 (Tmc2)", type "Antibodies"
Hosts (5)
Reactivities (3), (2), (1), (1), (1)
Applications (5), (1), (1), (1), (1)
Epitopes (1), (1), (1)
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