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Transmembrane Channel-Like 3 (Tmc3) (6th Cytoplasmic Loop) antibody

Details for Product No. ABIN351047, Supplier: Login to see
Antigen
  • 9030203A06
Epitope
6th Cytoplasmic Loop
1
Reactivity
Mouse (Murine)
1
Host
Rabbit
1
Clonality
Polyclonal
Application
Immunohistochemistry (IHC), Western Blotting (WB)
1
1
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Immunogen A synthetic from the 6th cytoplasmic loop of mouse transmembrane channel-like protein 3 (TMC3) conjugated to an immunogenic carrier protein was used as the antigen.
Specificity Specific for TMC3.
Purification Whole serum
Alternative Name TMC3
Background SUBCELLULAR LOCATION: Membrane, Multi-pass membrane protein.
Tissue specificity: Detected in most neuronal organs and also in some non-neuronal tissues. Also known as:transmembrane channel-like protein 3, Tmc3.
Pathways
Application Notes A dilution of 1 : 300 to 1 : 2000 is recommended.
The optimal dilution should be determined by the end user.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date 12 months
Background publications Carninci, Kasukawa, Katayama et al.: "The transcriptional landscape of the mammalian genome. ..." in: Science (New York, N.Y.), Vol. 309, Issue 5740, pp. 1559-63, 2005 (PubMed).

Kurima, Yang, Sorber et al.: "Characterization of the transmembrane channel-like (TMC) gene family: functional clues from hearing loss and epidermodysplasia verruciformis." in: Genomics, Vol. 82, Issue 3, pp. 300-8, 2003 (PubMed).

Keresztes, Mutai, Heller: "TMC and EVER genes belong to a larger novel family, the TMC gene family encoding transmembrane proteins." in: BMC genomics, Vol. 4, Issue 1, pp. 24, 2003 (PubMed).