Tmc4 antibody (Transmembrane Channel-Like 4) (1st Extracellular Loop)

Details for Product anti-Tmc4 Antibody No. ABIN351049, Supplier: Log in to see
Antigen
  • transmembrane channel-like 4
  • transmembrane channel-like gene family 4
  • TMC4
  • Tmc4
Epitope
1st Extracellular Loop
11
10
8
1
Reactivity
Human
20
1
Host
Rabbit
21
Clonality
Polyclonal
Conjugate
This Tmc4 antibody is un-conjugated
2
2
2
2
2
2
Application
Immunohistochemistry (IHC), Western Blotting (WB)
20
14
2
1
Options
Supplier
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Immunogen A synthetic peptide from the 1t extracellular loop of human transmembrane channel-like protein 4 (TMC4) conjugated to an immunogenic carrier protein was used as the immunogen.
Specificity Specific for TMC4.
Purification Whole serum
Alternative Name TMC4 (Tmc4 Antibody Abstract)
Background Function: May function as ion channels, transporters or modulators of such.
Subcellular location: Membrane, Multi-pass membrane protein.
Tissue specificity: Ubiquitously expressed. Also known as: TMC4.
Application Notes A dilution of 1 : 300 to 1 : 2000 is recommended.
The optimal dilution should be determined by the end user.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date 12 months
Background publications Keresztes, Mutai, Heller: "TMC and EVER genes belong to a larger novel family, the TMC gene family encoding transmembrane proteins." in: BMC genomics, Vol. 4, Issue 1, pp. 24, 2003 (PubMed).

Kurima, Yang, Sorber, Griffith: "Characterization of the transmembrane channel-like (TMC) gene family: functional clues from hearing loss and epidermodysplasia verruciformis." in: Genomics, Vol. 82, Issue 3, pp. 300-8, 2003 (PubMed).

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