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Transmembrane Channel-Like 4 (Tmc4) (1st Extracellular Loop) antibody

Details for Product No. ABIN351049, Supplier: Log in to see
Antigen
Epitope
1st Extracellular Loop
17
15
2
1
Reactivity
Human
19
1
Host
Rabbit
20
Clonality
Polyclonal
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
Immunohistochemistry (IHC), Western Blotting (WB)
18
14
1
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Immunogen A synthetic peptide from the 1t extracellular loop of human transmembrane channel-like protein 4 (TMC4) conjugated to an immunogenic carrier protein was used as the immunogen.
Specificity Specific for TMC4.
Purification Whole serum
Alternative Name TMC4 (Tmc4 Antibody Abstract)
Background Function: May function as ion channels, transporters or modulators of such.
Subcellular location: Membrane, Multi-pass membrane protein.
Tissue specificity: Ubiquitously expressed. Also known as: TMC4.
Application Notes A dilution of 1 : 300 to 1 : 2000 is recommended.
The optimal dilution should be determined by the end user.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date 12 months
Background publications Kurima, Yang, Sorber et al.: "Characterization of the transmembrane channel-like (TMC) gene family: functional clues from hearing loss and epidermodysplasia verruciformis." in: Genomics, Vol. 82, Issue 3, pp. 300-8, 2003 (PubMed).

Keresztes, Mutai, Heller: "TMC and EVER genes belong to a larger novel family, the TMC gene family encoding transmembrane proteins." in: BMC genomics, Vol. 4, Issue 1, pp. 24, 2003 (PubMed).