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Transmembrane Channel-Like 5 (Tmc5) (1st Extracellular Loop) antibody

Details for Product No. ABIN351050
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Antigen
Synonyms 4932443L08Rik, AU016085
Epitope
1st Extracellular Loop
(7), (6), (2), (1)
Reactivity
Human
(8), (1), (1)
Host
Rabbit
(10)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(10), (6), (3)
Pubmed 3 references available
Quantity 100 µL
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Catalog No. ABIN351050
454.67 $
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Immunogen A synthetic peptide from the 1t extracellular loop of human transmembrane channel-like protein 5 (TMC5) conjugated to an immunogenic carrier protein was used as the antigen.
Specificity Specific for TMC5.
Purification Whole serum
Alternative Name TMC5
Background Function: May function as ion channels, transporters or modulators of such.
Subcellular location: Membrane, Multi-pass membrane protein. Also known as:transmembrane channel-like protein 5, TMC5.
Application Notes A dilution of 1 : 400 to 1 : 2000 is recommended.
The optimal dilution should be determined by the end user.
Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date 12 months
General Keresztes, Mutai, Heller: "TMC and EVER genes belong to a larger novel family, the TMC gene family encoding transmembrane proteins." in: BMC genomics, Vol. 4, Issue 1, pp. 24, 2003 (PubMed).

Kurima, Yang, Sorber et al.: "Characterization of the transmembrane channel-like (TMC) gene family: functional clues from hearing loss and epidermodysplasia verruciformis." in: Genomics, Vol. 82, Issue 3, pp. 300-8, 2003 (PubMed).

Ota, Suzuki, Nishikawa et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003 (PubMed).

Validation Images
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