Transmembrane Channel-Like 5 (TMC5) (1st Extracellular Loop) antibody

Antigen: Transmembrane Channel-Like 5 (TMC5)

Synonyms: FLJ13593, AU016085, MGC118178, 4932443L08Rik

Binding Site: 1st Extracellular Loop

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Catalog no.: ABIN351051

Additional Information

Alternative name: transmembrane channel-like protein 5 (TMC5)

UniProt: Q6UXY8

Immunogen: A synthetic peptide from the 1t extracellular loop of human transmembrane channel-like protein 5 (TMC5) conjugated to an immunogenic carrier protein was used as the immunogen.

Format: Lyophilized

Description: FUNCTION: May function as ion channels, transporters or modulators of such. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. Also known as:transmembrane channel-like protein 5, TMC5.

Specificity: Appears to be specific for TMC5.

Application Details

Application Notes: IHC, WB. A dilution of 1 : 400 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Purity: whole serum

Storage: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Restrictions: For Research Use only

Publications

Keresztes, Mutai, Heller: "TMC and EVER genes belong to a larger novel family, the TMC gene family encoding transmembrane proteins." in: BMC genomics, Vol. 4, Issue 1, pp. 24, 2003 (PubMed).

Kurima, Yang, Sorber et al.: "Characterization of the transmembrane channel-like (TMC) gene family: functional clues from hearing loss and epidermodysplasia verruciformis." in: Genomics, Vol. 82, Issue 3, pp. 300-8, 2003 (PubMed).

Ota, Suzuki, Nishikawa et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003 (PubMed).