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Details for Product No. ABIN351057

Transmembrane Channel-Like 8 (TMC8) (1st Cytoplasmic Loop) antibody

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Antigen
Synonyms EV2, EVER2, EVIN2, Ever2, mFLJ00400
Epitope
»Alternatives 1st Cytoplasmic Loop
Reactivity
»Alternatives Mouse (Murine)
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 3 references available
Catalog no. ABIN351057
Quantity 100 µL
Price
454.67 $   Plus shipping costs $45.00
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Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide from the 1t cytoplasmic loop of mouse transmembrane channel-like protein 8 (TMC8, EVER2, EVIN2) conjugated to an immunogenic carrier protein was used as the immunogen.
Specificity Appears to be specific for TMC8.
Purity whole serum
Alternative Name transmembrane channel-like protein 8 (TMC8, EVER2, EVIN2)
Background SUBCELLULAR LOCATION: Endoplasmic reticulum membrane, Multi-pass membrane protein.
Tissue specificity: Expressed in placenta, prostate and testis. DISEASE: Defects in TMC8 are a cause of epidermodysplasia verruciformis. It is a rare autosomal recessive genodermatosis associated with a high risk of skin carcinoma that results from an abnormal susceptibility to infection by specific human papillomaviruses. Infection leads to persistent wart-like or macular lesions. Also known as: TMC8, Epidermodysplasia verruciformis protein 2, EVER2, EVIN2.
UniProt Q7TN58
Application Notes IHC, WB. A dilution of 1 : 400 to 1 : 5000 is recommended. The optimal dilution should be determined by the end user.
Restrictions For Research Use only
Format Lyophilized
Storage -20 °C
Keresztes, Mutai, Heller: "TMC and EVER genes belong to a larger novel family, the TMC gene family encoding transmembrane proteins." in: BMC genomics, Vol. 4, Issue 1, pp. 24, 2003 (PubMed).

Kurima, Yang, Sorber et al.: "Characterization of the transmembrane channel-like (TMC) gene family: functional clues from hearing loss and epidermodysplasia verruciformis." in: Genomics, Vol. 82, Issue 3, pp. 300-8, 2003 (PubMed).

Carninci, Kasukawa, Katayama et al.: "The transcriptional landscape of the mammalian genome." in: Science (New York, N.Y.), Vol. 309, Issue 5740, pp. 1559-63, 2005 (PubMed).

Alternatives for antigen "Transmembrane Channel-Like 8 (TMC8)", type "Antibodies"
Hosts (48)
Reactivities (47), (32), (32), (12)
Applications (34), (22), (13), (10), (8), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (14), (4), (3), (2), (2), (1), (1), (1), (1)
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