Search, Find and Buy Antibodies, ELISA Kits and Proteins.
Loading Loading
Order hotline:
phone +1 404 474 4654
fax +1 888 205 9894 (TF)
Details for Product No. ABIN351058

Transmembrane Channel-Like 8 (TMC8) (5th Cytoplasmic Loop) antibody

Request
Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms EV2, EVER2, EVIN2, Ever2, mFLJ00400
Epitope
»Alternatives 5th Cytoplasmic Loop
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 3 references available
Catalog no. ABIN351058
Quantity 100 µL
Price
454.67 $   Plus shipping costs $45.00
Shipping to
Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide from the 5th cytoplasmic loop of human transmembrane channel-like protein 8 (TMC8, EVER2, EVIN2) conjugated to an immunogenic carrier protein was used as the immunogen.
Specificity Appears to be specific for TMC8.
Purity whole serum
Alternative Name transmembrane channel-like protein 8 (TMC8, EVER2, EVIN2)
Background SUBCELLULAR LOCATION: Endoplasmic reticulum membrane, Multi-pass membrane protein.
Tissue specificity: Expressed in placenta, prostate and testis. DISEASE: Defects in TMC8 are a cause of epidermodysplasia verruciformis. It is a rare autosomal recessive genodermatosis associated with a high risk of skin carcinoma that results from an abnormal susceptibility to infection by specific human papillomaviruses. Infection leads to persistent wart-like or macular lesions. Also known as: TMC8, Epidermodysplasia verruciformis protein 2, EVER2, EVIN2.
UniProt Q8IU68
Application Notes IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user.
Restrictions For Research Use only
Format Lyophilized
Storage -20 °C
Ramoz, Rueda, Bouadjar et al.: "Mutations in two adjacent novel genes are associated with epidermodysplasia verruciformis." in: Nature genetics, Vol. 32, Issue 4, pp. 579-81, 2002 (PubMed).

Kurima, Yang, Sorber et al.: "Characterization of the transmembrane channel-like (TMC) gene family: functional clues from hearing loss and epidermodysplasia verruciformis." in: Genomics, Vol. 82, Issue 3, pp. 300-8, 2003 (PubMed).

Olsen, Blagoev, Gnad et al.: "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." in: Cell, Vol. 127, Issue 3, pp. 635-48, 2006 (PubMed).

Alternatives for antigen "Transmembrane Channel-Like 8 (TMC8)", type "Antibodies"
Hosts (48)
Reactivities (46), (33), (32), (12)
Applications (34), (22), (13), (10), (8), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (14), (4), (3), (2), (2), (2), (1), (1)
Beacon