Transient Receptor Potential A1 (TRPA1) (4th Extracellular Loop) antibody

Antigen: Transient Receptor Potential A1 (TRPA1)

Binding Site: 4th Extracellular Loop

Clonality: Polyclonal

Host: Rabbit

Reactivity: Fruit Fly (Drosophila melanogaster)

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Catalog no.: ABIN351112

Additional Information

Alternative name: TRPA1 (ANKTM1, dANKTM1)

UniProt: Q7Z020

Immunogen: A synthetic peptide from the 4th extracellular loop of drosophila TRPA1 (ANKTM1, dANKTM1) conjugated to an immunogenic carrier protein was used as the immunogen.

Format: Lyophilized

Description: FUNCTION: Receptor-activated non-selective cation channel involved in detection of sensations such as temperature. Involved in heat nociception by being activated by warm temperature of about 24-29 degrees Celsius. Also known as: Transient receptor potential cation channel subfamily A member 1, ankyrin-like withtransmembrane domains protein 1, Transient receptor potential A1, ANKTM1, dTRPA1.

Specificity: Appears to be specific for TRPA1.

Application Details

Application Notes: IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Purity: whole serum

Storage: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Restrictions: For Research Use only

Publications

Adams, Celniker, Holt et al.: "The genome sequence of Drosophila melanogaster." in: Science (New York, N.Y.), Vol. 287, Issue 5461, pp. 2185-95, 2000 (PubMed).

Viswanath, Story, Peier et al.: "Opposite thermosensor in fruitfly and mouse." in: Nature, Vol. 423, Issue 6942, pp. 822-3, 2003 (PubMed).