Transient Receptor Potential Cation Channel, Subfamily A, Member 1 (TRPA1) (1st Cytoplasmic Loop) antibody

Details for Product No. ABIN351113
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Antigen
Synonyms trpa1, ANKTM1, Anktm1, CG5751, CG5761, CT18073, DmTRPA1, Dmel\\CG5751, TRPA, TRPA1, TrpA, dANKTM1, dTRPA, dTRPA1, dTrpA, dTrpA1, dtrpA1, trpA1, GLEAN_02449, FEPS
Epitope
1st Cytoplasmic Loop
(13), (8), (6), (5), (5), (4), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Reactivity
Chicken
(40), (13), (8), (4), (3), (2), (2)
Host
Rabbit
(52), (6), (3)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(53), (30), (13), (5), (2), (1), (1), (1)
Pubmed 2 references available
Quantity 100 µL
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Catalog No. ABIN351113
454.67 $
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Immunogen A synthetic peptide from the 1t cytoplasmic loop of C. elegance TRPA1 (ANKTM1, trpa-1) conjugated to an immunogenic carrier protein was used as the antigen.
Specificity Specific for TRPA1.
Purification Whole serum
Alternative Name TRPA1
Background Function: Receptor-activated non-selective cation channel involved in the nose-touch response and foraging behavior. Contributes to the neural responses of sensory neurons to touch, particularly after repeated mechanical stimulation. Has no apparent role in thermosensory or chemosensory behaviors.
Subcellular location: Membrane, Multi-pass membrane protein.
Tissue specificity: Expressed in many sensory neurons, including OLQ and IL1 neurons.
Miscellaneous: Worms lacking trpa-1 exhibit specific defects in mechanosensory behaviors: abnormal head withdrawal reflex, defective reversal behavior in response to nose-touch and foraging behaviors. Also known as: Transient receptor potential cation channel subfamily A member 1, ankyrin-like withtransmembrane domains protein 1, transformation sensitive protein p120, ANKTM1, trpa-1.
Research Area Neurology
Application Notes A dilution of 1 : 300 to 1 : 2000 is recommended.
The optimal dilution should be determined by the end user.
Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date 12 months
General "Genome sequence of the nematode C. elegans: a platform for investigating biology." in: Science (New York, N.Y.), Vol. 282, Issue 5396, pp. 2012-8, 1998 (PubMed).

Kindt, Viswanath, Macpherson et al.: "Caenorhabditis elegans TRPA-1 functions in mechanosensation." in: Nature neuroscience, Vol. 10, Issue 5, pp. 568-77, 2007 (PubMed).

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