Transient Receptor Potential Cation Channel, Subfamily A, Member 1 (TRPA1) (Cytoplasmic Loop) antibody

Details for Product No. ABIN351114
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Antigen
Synonyms ANKTM1, FEPS, Anktm1, trpa1, CG5751, CG5761, CT18073, DmTRPA1, Dmel\\CG5751, TRPA, TRPA1, TrpA, dANKTM1, dTRPA, dTRPA1, dTrpA, dTrpA1, dtrpA1, trpA1, GLEAN_02449
Epitope
Cytoplasmic Loop
(13), (10), (7), (6), (5), (3), (2), (2), (1), (1), (1), (1)
Reactivity
Human
(45), (24), (14), (4), (2), (1), (1)
Host
Rabbit
(62), (3), (2), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (1), (1)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(54), (27), (26), (6), (4), (3), (2), (2), (1), (1)
Pubmed 2 references available
Catalog no. ABIN351114
Quantity 500 µg
Price
454.67 $   Plus shipping costs $45.00
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Immunogen A synthetic peptide from the 1t cytoplasmic loop of C. Elegance TRPA1 (ANKTM1, trpa-1) conjugated to an immunogenic carrier protein was used as the immunogen.
Specificity Specific for PK1L1.
Purification IgG
Alternative Name TRPA1 (ANKTM1,TRPa-1)
Background Function: Receptor-activated non-selective cation channel involved in the nose-touch response and foraging behavior. Contributes to the neural responses of sensory neurons to touch, particularly after repeated mechanical stimulation. Has no apparent role in thermosensory or chemosensory behaviors.
Subcellular location: Membrane, Multi-pass membrane protein.
Tissue specificity: Expressed in many sensory neurons, including OLQ and IL1 neurons.
Miscellaneous: Worms lacking trpa-1 exhibit specific defects in mechanosensory behaviors: abnormal head withdrawal reflex, defective reversal behavior in response to nose-touch and foraging behaviors. Also known as: Transient receptor potential cation channel subfamily A member 1, ankyrin-like withtransmembrane domains protein 1, transformation sensitive protein p120, ANKTM1, trpa-1.
UniProt Q8TDX9
Research Area Signaling, Metabolism
Application Notes A concentration of 10 to 50 µg/mL is recommended.
The optimal dilution should be determined by the end user.
Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage -20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20 °C for long term storage and refrigerated at 2-8 °C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability.
Expiry Date 12 months
General "Genome sequence of the nematode C. elegans: a platform for investigating biology." in: Science (New York, N.Y.), Vol. 282, Issue 5396, pp. 2012-8, 1998 (PubMed).

Kindt, Viswanath, Macpherson et al.: "Caenorhabditis elegans TRPA-1 functions in mechanosensation." in: Nature neuroscience, Vol. 10, Issue 5, pp. 568-77, 2007 (PubMed).

Hosts (62), (3), (2), (1)
Reactivities (45), (24), (14), (4), (2), (1), (1)
Applications (54), (27), (26), (6), (4), (3), (2), (2), (1), (1)
Conjugates (2), (2), (2), (1), (1)
Epitopes (13), (10), (7), (6), (5), (3), (2), (2), (1), (1), (1), (1)
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