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Details for Product No. ABIN351116

Transient Receptor Potential Cation Channel, Subfamily A, Member 1 (TRPA1) (Cytoplasmic Loop) antibody

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Antigen
Synonyms ANKTM1, FEPS, Anktm1, trpa1, CG5751, CG5761, CT18073, DmTRPA1, Dmel\\CG5751, TRPA, TRPA1, TrpA, dANKTM1, dTRPA, dTRPA1, dTrpA, dTrpA1, dtrpA1, trpA1, GLEAN_02449
Epitope
»Alternatives Cytoplasmic Loop
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 2 references available
Catalog no. ABIN351116
Quantity 100 µL
Price
454.67 $   Plus shipping costs $45.00
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Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide from the 1t cytoplasmic loop of C. elegance TRPA1 (ANKTM1, trpa-1) conjugated to an immunogenic carrier protein was used as the antigen.
Specificity Specific for TMC8.
Purity IgG
Alternative Name TRPA1 (ANKTM1,TRPa-1)
Background Function: Receptor-activated non-selective cation channel involved in the nose-touch response and foraging behavior. Contributes to the neural responses of sensory neurons to touch, particularly after repeated mechanical stimulation. Has no apparent role in thermosensory or chemosensory behaviors.
Subcellular location: Membrane, Multi-pass membrane protein.
Tissue specificity: Expressed in many sensory neurons, including OLQ and IL1 neurons.
Miscellaneous: Worms lacking trpa-1 exhibit specific defects in mechanosensory behaviors: abnormal head withdrawal reflex, defective reversal behavior in response to nose-touch and foraging behaviors. Also known as: Transient receptor potential cation channel subfamily A member 1, ankyrin-like withtransmembrane domains protein 1, transformation sensitive protein p120, ANKTM1, trpa-1.
UniProt Q8IU68
Application Notes A concentration of 10-50 µg/mL is recommended.
The optimal concentration should be determined by the end user.
Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage -20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20 °C for long term storage and refrigerated at 2-8 °C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability.
Expiry Date 12 months
"Genome sequence of the nematode C. elegans: a platform for investigating biology." in: Science (New York, N.Y.), Vol. 282, Issue 5396, pp. 2012-8, 1998 (PubMed).

Kindt, Viswanath, Macpherson et al.: "Caenorhabditis elegans TRPA-1 functions in mechanosensation." in: Nature neuroscience, Vol. 10, Issue 5, pp. 568-77, 2007 (PubMed).

Alternatives for antigen "Transient Receptor Potential Cation Channel, Subfamily A, Member 1 (TRPA1)", type "Antibodies"
Hosts (65), (3), (3)
Reactivities (47), (25), (14), (4), (2), (1), (1)
Applications (59), (32), (29), (8), (7), (3), (2), (2), (2), (1)
Conjugates (2), (2), (2), (1), (1)
Epitopes (12), (12), (11), (8), (6), (5), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
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