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TRPC1 antibody (Extracellular Loop)

TRPC1 Reactivity: Human, Mouse, Rat WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN351118
  • Target See all TRPC1 Antibodies
    TRPC1 (Transient Receptor Potential Cation Channel, Subfamily C, Member 1 (TRPC1))
    Binding Specificity
    • 16
    • 11
    • 8
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 500-540, Extracellular Loop
    Reactivity
    • 50
    • 7
    • 6
    • 1
    Human, Mouse, Rat
    Host
    • 47
    • 2
    • 1
    • 1
    Rabbit
    Clonality
    • 49
    • 2
    Polyclonal
    Conjugate
    • 23
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TRPC1 antibody is un-conjugated
    Application
    • 29
    • 27
    • 15
    • 8
    • 6
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Specificity
    Specific for TRPC1.
    Immunogen
    A synthetic peptide from aa region 500-540 of the 2d extracellular loop of human TRPC1 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat and mouse.
    Isotype
    IgG
    Top Product
    Discover our top product TRPC1 Primary Antibody
  • Application Notes
    A concentration of 10-50 µg/ml is recommended.
    The optimal concentration should be determined by the end user.
    Not yet tested in other applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
    Handling Advice
    Avoid freeze and thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
    Expiry Date
    12 months
  • Target
    TRPC1 (Transient Receptor Potential Cation Channel, Subfamily C, Member 1 (TRPC1))
    Alternative Name
    TRPC1 (TRPC1 Products)
    Synonyms
    HTRP-1 antibody, TRP1 antibody, Trrp1 antibody, xtrpc1 antibody, Mtrp1 antibody, Trp1 antibody, Trpc1 antibody, transient receptor potential cation channel subfamily C member 1 antibody, transient receptor potential cation channel, subfamily C, member 1 antibody, transient receptor potential cation channel, subfamily C, member 1 L homeolog antibody, TRPC1 antibody, Trpc1 antibody, trpc1.L antibody, trpc1 antibody
    Background
    Function: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion.
    Subunit: Interacts with TRPC3. Interacts with ITPR3.
    Subcellular location: Membrane, Multi-pass membrane protein.
    Tissue specificity: Seems to be ubiquitous. Also known as: Short transient receptor potential channel 1, TrpC1, TRP-1 protein, Trp1, Trrp1, Trpc1 transient receptor potential cation channel, subfamily C, member 1, Mtrp1, Trp-related protein 1.
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