Transient Receptor Potential Cation Channel, Subfamily C, Member 2, Pseudogene (TRPC2) antibody

Antigen: Transient Receptor Potential Cation Channel, Subfamily C, Member 2, Pseudogene (TRPC2)

Synonyms: trp2, Trrp2, mTrp2, TRPC2a, TRPC2b, smTRPC2, AI115608, 3010009O07Rik, MGC189397, SCE8.04c, trpC2, RS01769

Clonality: Polyclonal

Host: Rabbit

Reactivity: Rat (Rattus)

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Catalog no.: ABIN351123

Additional Information

Alternative name: TRPC2

UniProt: Q9R283

Immunogen: A synthetic peptide from rat TRPC2, conjugated to an immunogenic carrier protein was used as the immunogen.

Format: Lyophilized

Description: FUNCTION: Thought to form a receptor-activated calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Is not activated by intracellular calcium store depletion. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein (Probable). TISSUE SPECIFICITY: Expressed exclusively invomeronasal organ neurons (sensory microvilli). SIMILARITY: Belongs to the transient receptor family, STrpC subfamily. SIMILARITY: Contains 3 ANK repeats Also known as: Short transient receptor potential channel 2, rTRP2, Trp2, Trpc2 transient receptor potential cation channel, subfamily C, member 2, Trrp2.

Specificity: Appears to be specific for TRPC2.

Application Details

Application Notes: IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Purity: whole serum

Storage: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Research Area: Neurology

Restrictions: For Research Use only

Publications

Liman, Corey, Dulac: "TRP2: a candidate transduction channel for mammalian pheromone sensory signaling." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 10, pp. 5791-6, 1999 (PubMed).