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Details for Product No. ABIN351124

Transient Receptor Potential Cation Channel, Subfamily C, Member 2, Pseudogene (TRPC2) antibody

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Antigen
Synonyms trp2, Trrp2, mTrp2, TRPC2a, TRPC2b, smTRPC2, AI115608, 3010009O07Rik, SCE8.04c, trpC2, RS01769
Reactivity
»Alternatives Mouse (Murine)
Host
»Alternatives Sheep
Clonality Polyclonal
Application
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 6 references available
Catalog no. ABIN351124
Quantity 100 µL
Price
454.67 $   Plus shipping costs $45.00
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Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide as a part of mouse TRPC2, conjugated to an immunogenic carrier protein was used as the immunogen.
Specificity Appears to be specific for TRPC2.
Purity whole serum
Alternative Name TRPC2
Background Function: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. May also be activated by intracellular calcium store depletion.
Subcellular location: Membrane, Multi-pass membrane protein (Probable). Also known as: Short transient receptor potential channel 2, mTrp2, Trp2, Trrp2, Trpc2, transient receptor potential cation channel, subfamily C, member 2, trp2, Trrp2, mTrp2, TRPC2a, TRPC2b, smTRPC2, AI115608, 3010009O07Rik.
UniProt Q9R244
Research Area Neurology
Application Notes IHC, WB. A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Storage -20 °C
Vannier, Peyton, Boulay et al.: "Mouse trp2, the homologue of the human trpc2 pseudogene, encodes mTrp2, a store depletion-activated capacitative Ca2+ entry channel." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 5, pp. 2060-4, 1999 (PubMed).

Hofmann, Schaefer, Schultz et al.: "Cloning, expression and subcellular localization of two novel splice variants of mouse transient receptor potential channel 2." in: The Biochemical journal, Vol. 351, Issue Pt 1, pp. 115-22, 2001 (PubMed).

Stamboulian, Moutin, Treves et al.: "Junctate, an inositol 1,4,5-triphosphate receptor associated protein, is present in rodent sperm and binds TRPC2 and TRPC5 but not TRPC1 channels." in: Developmental biology, Vol. 286, Issue 1, pp. 326-37, 2005 (PubMed).

Ramsey, Delling, Clapham: "An introduction to TRP channels." in: Annual review of physiology, Vol. 68, pp. 619-47, 2006 (PubMed).

Kelliher, Spehr, Li et al.: "Pheromonal recognition memory induced by TRPC2-independent vomeronasal sensing." in: The European journal of neuroscience, Vol. 23, Issue 12, pp. 3385-90, 2006 (PubMed).

Kimchi, Xu, Dulac: "A functional circuit underlying male sexual behaviour in the female mouse brain." in: Nature, Vol. 448, Issue 7157, pp. 1009-14, 2007 (PubMed).

Alternatives for antigen "Transient Receptor Potential Cation Channel, Subfamily C, Member 2, Pseudogene (TRPC2)", type "Antibodies"
Hosts (6), (1)
Reactivities (3), (2), (1), (1)
Applications (7), (6), (1), (1)
Epitopes (1)
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