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Details for Product No. ABIN351149

Transient Receptor Potential Cation Channel, Subfamily C, Member 4 Associated Protein (TRPC4AP) (N-Term) antibody

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Antigen
Synonyms TRUSS, TRRP4AP, C20orf188, 4833429F06Rik, D2Ertd113e, Trrp4ap, mFLJ00177, truss, TRPC4AP, MGC130977
Epitope
»Alternatives N-Term
Reactivity
»Alternatives Human, Mouse (Murine)
Host
»Alternatives Rabbit
Clonality Polyclonal
Application
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 5 references available
Catalog no. ABIN351149
Quantity 100 µL
Price
454.67 $   Plus shipping costs $45.00
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Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide from the internal part of human TRPC4AP (TRUSS) conjugated to an immunogenic carrier protein was used as the immunogen. The antigen shares 95% identity with mouse's.
Specificity Appears to be specific for TRPC4AP.
Purity whole serum
Alternative Name TRPC4AP (TRUSS)
Background Function: May participate in the activation of NFKB1 in response to ligation of TNFRSF1A. Could serve as a scaffolding protein to link TNFRSF1A to the IKK signalosome.
Subunit: Constitutively associated with TNFRSF1A. Directly interacts with TRADD, TRAF2, CHUK, IKBKB and IKBKG. Also known as: Trpc4-associated protein, TRUSS, short transient receptor potential channel 4-associated protein, Trp4-associated protein, TAP1 protein, TNF-receptor ubiquitous scaffolding/signaling protein, C20orf188, TRRP4AP, TP4AP, Rabex-5/Rin2-interacting protein.
UniProt Q8TEL6
Application Notes IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Storage -20 °C
Deloukas, Matthews, Ashurst et al.: "The DNA sequence and comparative analysis of human chromosome 20." in: Nature, Vol. 414, Issue 6866, pp. 865-71, 2002 (PubMed).

Antoniou, Ford, Pilley et al.: "Interactions formed by individually expressed TAP1 and TAP2 polypeptide subunits." in: Immunology, Vol. 106, Issue 2, pp. 182-9, 2002 (PubMed).

Jikuya, Takano, Kikuno et al.: "Characterization of long cDNA clones from human adult spleen. II. The complete sequences of 81 cDNA clones." in: DNA research : an international journal for rapid publication of reports on genes and genomes, Vol. 10, Issue 1, pp. 49-57, 2003 (PubMed).

Soond, Terry, Colbert et al.: "TRUSS, a novel tumor necrosis factor receptor 1 scaffolding protein that mediates activation of the transcription factor NF-kappaB." in: Molecular and cellular biology, Vol. 23, Issue 22, pp. 8334-44, 2003 (PubMed).

Tsang, Connell, Brown et al.: "A systematic analysis of human CHMP protein interactions: additional MIT domain-containing proteins bind to multiple components of the human ESCRT III complex." in: Genomics, Vol. 88, Issue 3, pp. 333-46, 2006 (PubMed).

Alternatives for antigen "Transient Receptor Potential Cation Channel, Subfamily C, Member 4 Associated Protein (TRPC4AP)", type "Antibodies"
Hosts (14), (4), (2), (1)
Reactivities (19), (10), (9), (1), (1)
Applications (18), (6), (6), (2), (2), (1)
Epitopes (4), (3), (2), (2), (2), (1), (1), (1)
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