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|+1 404 474 4654|
|+1 888 205 9894 (TF)|
Transient Receptor Potential Cation Channel, Subfamily C, Member 4 Associated Protein (TRPC4AP) (N-Term) antibody
|Synonyms||TRUSS, TRRP4AP, C20orf188, truss, Trrp4ap, FLJ00177, mFLJ00177, D2Ertd113e, 4833429F06Rik, TRPC4AP, MGC130977|
Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
|5 references available|
|Price||454.67 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 7 to 8 Business Days|
|Alternative name||TRPC4AP (TRUSS)|
|Immunogen||A synthetic peptide from the internal part of human TRPC4AP (TRUSS) conjugated to an immunogenic carrier protein was used as the immunogen. The antigen shares 95% identity with mouse's.|
|Description||FUNCTION: May participate in the activation of NFKB1 in response to ligation of TNFRSF1A. Could serve as a scaffolding protein to link TNFRSF1A to the IKK signalosome. SUBUNIT: Constitutively associated with TNFRSF1A. Directly interacts with TRADD, TRAF2, CHUK, IKBKB and IKBKG. Also known as: Trpc4-associated protein, TRUSS, short transient receptor potential channel 4-associated protein, Trp4-associated protein, TAP1 protein, TNF-receptor ubiquitous scaffolding/signaling protein, C20orf188, TRRP4AP, TP4AP, Rabex-5/Rin2-interacting protein.|
|Specificity||Appears to be specific for TRPC4AP.|
|Application Notes||IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.|
|Storage||Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.|
|Restrictions||For Research Use only|
Deloukas, Matthews, Ashurst et al.: "The DNA sequence and comparative analysis of human chromosome 20." in: Nature, Vol. 414, Issue 6866, pp. 865-71, 2002 (PubMed).
Antoniou, Ford, Pilley et al.: "Interactions formed by individually expressed TAP1 and TAP2 polypeptide subunits." in: Immunology, Vol. 106, Issue 2, pp. 182-9, 2002 (PubMed).
Jikuya, Takano, Kikuno et al.: "Characterization of long cDNA clones from human adult spleen. II. The complete sequences of 81 cDNA clones." in: DNA research : an international journal for rapid publication of reports on genes and genomes, Vol. 10, Issue 1, pp. 49-57, 2003 (PubMed).
Soond, Terry, Colbert et al.: "TRUSS, a novel tumor necrosis factor receptor 1 scaffolding protein that mediates activation of the transcription factor NF-kappaB." in: Molecular and cellular biology, Vol. 23, Issue 22, pp. 8334-44, 2003 (PubMed).
Tsang, Connell, Brown et al.: "A systematic analysis of human CHMP protein interactions: additional MIT domain-containing proteins bind to multiple components of the human ESCRT III complex." in: Genomics, Vol. 88, Issue 3, pp. 333-46, 2006 (PubMed).
|Hosts||Rabbit (13), Goat (1), Mouse (1), Sheep (1)|
|Reactivities||Human (10), Mouse (Murine) (4), Rat (Rattus) (4), Dog (Canine) (1)|
|Applications||Western Blotting (WB) (13), Immunohistochemistry (IHC) (9), ELISA (8)|
|Epitopes||Internal Region (3), C-Term (1), N-Term,AA 48-75 (1)|