TRPC5 antibody (4th Cytoplasmic Domain, Trp5)

Catalog No. ABIN351153

Product Details anti-TRPC5 Antibody

Target: TRPC5 (Transient Receptor Potential Cation Channel, Subfamily C, Member 5 (TRPC5))

Binding Specificity: 4th Cytoplasmic Domain, Trp5

Reactivity: Human

Host: Sheep

Clonality: Polyclonal

Conjugate: This TRPC5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificity: Specific for TRPC5.

Cross-Reactivity: Human

Cross-Reactivity (Details): Other species not yet tested.

Purification: IgG

Immunogen: A synthetic peptide from 4th cytoplasmic domain of human TRPC5 (TRP5) conjugated to an immunogenic carrier protein was used as the immunogen.

Isotype: IgG

Application Details

Application Notes: IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.

Handling Advice: Avoid freeze and thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date: 12 months

Target Details for TRPC5

Target: TRPC5 (Transient Receptor Potential Cation Channel, Subfamily C, Member 5 (TRPC5))

Alternative Name: TRPC5 (TRPC5 Products)

Synonyms: trpc5 antibody, wu:fi73f08 antibody, TRPC5 antibody, Trpc5 antibody, TRP5 antibody, CCE2 antibody, TRP-5 antibody, Trrp5 antibody, trp antibody, transient receptor potential cation channel, subfamily C, member 5a antibody, transient receptor potential cation channel subfamily C member 5 antibody, transient receptor potential cation channel, subfamily C, member 5 antibody, trpc5a antibody, TRPC5 antibody, Trpc5 antibody

Background: FUNCTION: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Has also been shown to be calcium-selective. May also be activated by intracellular calcium store depletion. SUBUNIT: Interacts with NHERF. SUBCELLULAR LOCATION: Membrane, Multi-pass membrane protein. TISSUE SPECIFICITY: Expressed in brain with higher levels in fetal brain.,Mammalian TRPC,Short transient receptor potential channel 5, TrpC5, Htrp-5, trp5, TRP5

UniProt: Q9UL62