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Transient Receptor Potential Cation Channel, Subfamily C, Member 5 (TRPC5) antibody

Antigen

Transient Receptor Potential Cation Channel, Subfamily C, Member 5 (TRPC5)
Synonyms TRP5, CCE2, TRP-5, Trrp5, MGC124500, TRPC5, trp, wu:fi73f08
Clonality Polyclonal
Host
Alternatives

Rabbit
Reactivity
Alternatives

Human
Application
Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
2 references available
Catalog no. ABIN351154
Quantity 100 µl  (Variants)
Price 413.33 $   Plus shipping costs $35.00
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Additional Information
Application Details Publications Alternatives Secondary Antibodies Variants back to top

Alternative name TRPC5 (TRP5, Htrp-5, Htrp5)
Swiss-Prot Q9UL62
Immunogen A synthetic peptide from human TRPC5 (TRP5, Htrp-5, Htrp5) conjugated to an immunogenic carrier protein was used as the immunogen.
Format Lyophilized
Description FUNCTION: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Has also been shown to be calcium-selective. May also be activated by intracellular calcium store depletion. SUBUNIT: Interacts with NHERF. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. TISSUE SPECIFICITY: Expressed in brain with higher levels in fetal brain. Also known as: Short transient receptor potential channel 5, TrpC5, Htrp-5, trp5, TRP5.
Specificity Appears to be specific for TRPC5.

Application Details
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Application Notes IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Purity whole serum
Storage Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Restrictions For Research Use only

Publications
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Publications Sossey-Alaoui, Lyon, Jones et al.: "Molecular cloning and characterization of TRPC5 (HTRP5), the human homologue of a mouse brain receptor-activated capacitative Ca2+ entry channel." in: Genomics, Vol. 60, Issue 3, pp. 330-40, 1999 (PubMed).

Ross, Grafham, Coffey et al.: "The DNA sequence of the human X chromosome." in: Nature, Vol. 434, Issue 7031, pp. 325-37, 2005 (PubMed).

Alternatives
Application Details Publications Secondary Antibodies Variants back to top

Alternatives for antigen "Transient Receptor Potential Cation Channel, Subfamily C, Member 5 (TRPC5)", type "Antibodies"
Hosts Rabbit (8), Mouse (5), Sheep (3)
Reactivities Human (9), Mouse (Murine) (3), Zebrafish (Danio rerio) (3), Cow (Bovine) (1), Rat (Rattus) (1)
Applications Western Blotting (WB) (14), Immunohistochemistry (IHC) (7), Immunohistochemistry (Frozen Sections) (IHC (fro)) (3), ELISA (2), Enzyme Immunoassay (EIA) (2), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (2), ELISA (Detection) (1), Immunofluorescence (IF) (1), Immunoprecipitation (IP) (1)
Epitopes 4th cytoplasmic loop (2), AA 827-845 (1)