Transient Receptor Potential Cation Channel, Subfamily C, Member 5 (TRPC5) antibody
| Antigen |
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| Synonyms |
TRP5, CCE2, TRP-5, Trrp5, MGC124500, TRPC5, trp, wu:fi73f08 |
| Clonality |
Polyclonal |
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Host
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Reactivity
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Application
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 Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
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| Catalog no. |
ABIN351156 |
| Quantity |
500 µg (Variants) |
| Price |
454.67 $ Plus shipping costs $45.00
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Bulk discount
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| Shipping to |
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| Availability |
Will be delivered in 7 to 8 Business Days |
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Alternative name
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TRPC5 (TRP5, Htrp-5, Htrp5)
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UniProt
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Q9UL62
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Immunogen
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A synthetic peptide as a part of human TRPC5 (TRP5, Htrp-5, Htrp5) conjugated to immunogenic carrier protein was used as the immunogen.
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Format
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Lyophilized
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Isotype
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IgG
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Description
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FUNCTION: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Has also been shown to be calcium-selective. May also be activated by intracellular calcium store depletion. SUBUNIT: Interacts with NHERF. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. TISSUE SPECIFICITY: Expressed in brain with higher levels in fetal brain. Also known as: Short transient receptor potential channel 5, TrpC5, Htrp-5, trp5, TRP5.
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Specificity
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Appears to be specific for TRPC5.
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Application Notes
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IHC, WB. A concentration of 10-50 µg/ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
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Purity
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IgG
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Storage
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Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
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Restrictions
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For Research Use only
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Sossey-Alaoui, Lyon, Jones et al.: "Molecular cloning and characterization of TRPC5 (HTRP5), the human homologue of a mouse brain receptor-activated capacitative Ca2+ entry channel." in: Genomics, Vol. 60, Issue 3, pp. 330-40, 1999 (PubMed).
Ross, Grafham, Coffey et al.: "The DNA sequence of the human X chromosome." in: Nature, Vol. 434, Issue 7031, pp. 325-37, 2005 (PubMed).
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Alternatives for antigen "Transient Receptor Potential Cation Channel, Subfamily C, Member 5 (TRPC5)", type "Antibodies"
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Hosts
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Rabbit (10), Mouse (8), Sheep (4)
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Reactivities
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Human (12), Mouse (Murine) (6), Rat (Rattus) (4), Zebrafish (Danio rerio) (3), Cow (Bovine) (1), Guinea Pig (1)
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Applications
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Western Blotting (WB) (21), Immunohistochemistry (IHC) (13), ELISA (5), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (4), Immunocytochemistry (ICC) (3), Immunofluorescence (IF) (3), Immunohistochemistry (Fixed) (IHC (fx)) (3), Immunoprecipitation (IP) (3), Immunostaining (ISt) (2), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1)
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Epitopes
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4th Cytoplasmic Loop (2), AA 827-845 (2), 4th Cytoplasmic Domain (1), AA 534-604 (1), AA 927-845 (1), N-Term (1), N-Term,AA 253-283 (1)
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