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Antibodies
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anti-Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6) (4...
Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6) (4th cytoplasmic domain) antibody
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| Synonyms |
TRP6, FSGS2, FLJ11098, FLJ14863, Trrp6, mtrp6, AV025995, LLHWJM002, LLHWJM003, LLHWJM004, TRPC6, trp6, trpc6, bZ1P14.9, si:rp71-1p14.9, Trpc6 |
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Epitope
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| Clonality |
Polyclonal |
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Host
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Reactivity
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Application
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 Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Western Blotting (WB) (40), Flow Cytometry (FACS) (20), Immunofluorescence (IF) (19), Immunohistochemistry (IHC) (14), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (10), Enzyme Immunoassay (EIA) (7), ELISA (6), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunohistochemistry (Frozen Sections) (IHC (fro)) (2), Immunoprecipitation (IP) (2), Immunocytochemistry (ICC) (1), Immunoelectron Microscopy (IEM) (1)
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| Catalog no. |
ABIN351165 |
| Quantity |
100 µl (Variants) |
| Price |
413.33 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 7 to 10 Business Days |
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Alternative name
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TRPC6, 3, 7 (4th cytoplasmic domain)
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Swiss-Prot
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Q9ESX7
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Immunogen
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A synthetic peptide from 4th cytoplasmic domain of guinea pig TRPC6 conjugated to an immunogenic carrier protein was used as the immunogen.
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Format
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Lyophilized
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Description
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FUNCTION: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C. Seems not to be activated by intracellular calcium store depletion. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. Also known as: TRPC6 cation channel, putative alternative splice variant gpTRPC6c, trp6.
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Specificity
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Appears to recognise TRPC6, TRPC3 and TRPC7.
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Application Notes
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IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
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Purity
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whole serum
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Storage
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Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
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Restrictions
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For Research Use only
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Alternatives for antigen "Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6)", type "Antibodies"
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Hosts
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Rabbit (50), Goat (6), Mouse (3), Sheep (3), Guinea Pig (1)
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Reactivities
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Human (42), Mouse (Murine) (37), Rat (Rattus) (31), Cow (Bovine) (18), Dog (Canine) (18), Guinea Pig (17), Horse (Equine) (16), Pig (Porcine) (16), Rabbit (16), Zebrafish (Danio rerio) (3)
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Applications
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Western Blotting (WB) (40), Flow Cytometry (FACS) (20), Immunofluorescence (IF) (19), Immunohistochemistry (IHC) (14), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (10), Enzyme Immunoassay (EIA) (7), ELISA (6), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunohistochemistry (Frozen Sections) (IHC (fro)) (2), Immunoprecipitation (IP) (2), Immunocytochemistry (ICC) (1), Immunoelectron Microscopy (IEM) (1)
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Conjugates
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Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
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Epitopes
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C-Term (7), 4th cytoplasmic loop (5), N-Term (3), 4th cytoplasmic domain (2), 1st cytoplasmic loop (1), 4th cytoplasmic loop pS814 (1)
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