TRPG (Transient receptor potential-gamma protein) (4th Cytoplasmic Loop) antibody

Antigen: TRPG (Transient receptor potential-gamma protein)

Binding Site: 4th Cytoplasmic Loop

Clonality: Polyclonal

Host: Rabbit

Reactivity: Fruit Fly (Drosophila melanogaster)

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Catalog no.: ABIN351173

Additional Information

UniProt: Q9VJJ7

Immunogen: A synthetic peptide from 4th cytoplasmic loop of drosophila TRPG (Transient receptor potential-gamma protein, TRPgamma) conjugated to an immunogenic carrier protein was used as the immunogen.

Format: Lyophilized

Isotype: IgG

Description: FUNCTION: A light-sensitive calcium channel that is required for inositide-mediated Ca(2+) entry in the retina during phospholipase C (PLC)-mediated phototransduction. Forms a regulated cation channel when heteromultimerized with trpl. SUBUNIT: Interacts preferentially with trpl and interacts to a lower extent with trp. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. TISSUE SPECIFICITY: Expressed predominantly in the rhabdomeres of photoreceptor cells. Also known as: TRPG, Transient receptor potential-gamma protein, TRPgamma.

Specificity: Appears to be specific for TRPG.

Application Details

Application Notes: IHC, WB. A concentration of 10-50 µg/ml is recommended. The optimal concentration should be determined by the end user.

Purity: IgG

Storage: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Restrictions: For Research Use only

Publications

Adams, Celniker, Holt et al.: "The genome sequence of Drosophila melanogaster." in: Science (New York, N.Y.), Vol. 287, Issue 5461, pp. 2185-95, 2000 (PubMed).

Xu, Chien, Butler et al.: "TRPgamma, a drosophila TRP-related subunit, forms a regulated cation channel with TRPL." in: Neuron, Vol. 26, Issue 3, pp. 647-57, 2000 (PubMed).