Transient Receptor Potential Cation Channel, Subfamily M, Member 1 (TRPM1) (4th Cytoplasmic Loop) antibody

Details for Product No. ABIN351185
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Antigen
Synonyms CSNB1C, LTRPC1, MLSN1, Mlsn1, Ltrpc1, AI606771, melastatin, 4732499L03Rik, TRPM1b, trpm1, zgc:158632
Epitope
4th Cytoplasmic Loop
(4), (1)
Reactivity
Human
(23), (22), (21), (17), (17), (17), (17), (3), (1)
Host
Rabbit
(25), (3), (1), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(16), (15), (10), (10), (6), (5), (2), (2)
Pubmed 3 references available
Catalog no. ABIN351185
Quantity 100 µL
Price
454.67 $   Plus shipping costs $45.00
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Immunogen A synthetic peptide from the 4th cytoplasmic loop of human TRPM1 (LTRPC1, MLSN1, melastatin-1) conjugated to an immunogenic carrier protein was used as the immunogen.
Isotype IgG
Specificity Specific for VAMP5.
Purification whole serum
Alternative Name TRPM1 (LTRPC1, MLSN1, melastatin-1)
Background The protein encoded by this gene is similar to the transient receptor potential (Trp) calcium channel family members. The expression of this protein is inversely correlated with melanoma aggressiveness, suggesting that it suppresses melanoma metastasis. Also known as: Transient receptor potential cation channel subfamily M member 1, TRPM1, MLSN1, LTRPC1, melastatin-1, melastatin 1.
UniProt O95183
Application Notes A dilution of 1 : 300 to 1 : 3000 is recommended.
The optimal dilution should be determined by the end user.
Restrictions For Research Use only
Format Liquid
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage -20 °C
Storage Comment Maintain the reconstituted antibodies frozen at -20 °C for long term storage and refrigerated at 2-8 °C for a shorter term.
Expiry Date 12 months
General Duncan, Deeds, Hunter et al.: "Down-regulation of the novel gene melastatin correlates with potential for melanoma metastasis." in: Cancer research, Vol. 58, Issue 7, pp. 1515-20, 1998 (PubMed).

Hunter, Shao, Smutko et al.: "Chromosomal localization and genomic characterization of the mouse melastatin gene (Mlsn1)." in: Genomics, Vol. 54, Issue 1, pp. 116-23, 1999 (PubMed).

Clapham, Julius, Montell et al.: "International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels." in: Pharmacological reviews, Vol. 57, Issue 4, pp. 427-50, 2005 (PubMed).

Hosts (25), (3), (1), (1)
Reactivities (23), (22), (21), (17), (17), (17), (17), (3), (1)
Applications (16), (15), (10), (10), (6), (5), (2), (2)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (4), (1)
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