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Details for Product No. ABIN351327

Vacuolar Protein Sorting 37 Homolog A (S. Cerevisiae) (VPS37A) (C-Term) antibody

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Antigen
Synonyms AW261445, D8Ertd531e, 2210018P21Rik, 4930592A21Rik, HCRP1, PQBP2, SPG53, fb08f03, fj42c03, zgc:73244, zgc:77637, wu:fb08f03, wu:fj42c03
Epitope
»Alternatives C-Term
Reactivity
»Alternatives Human, Rat (Rattus), Mouse (Murine)
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 5 references available
Catalog no. ABIN351327
Quantity 100 µL
Price
454.67 $   Plus shipping costs $45.00
Shipping to
Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide from the c-terminal of human Vacuolar protein sorting-associated protein 37A (VPS37A, Hepatocellular carcinoma-related protein 1) conjugated to an immunogenic carrier protein was used as the immunogen. The antigen is homologous in rat and mouse.
Specificity Appears to be specific for VPS37A.
Purity whole serum
Alternative Name Vacuolar protein sorting associated protein 37A (VPS37A)
Background Function: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
Subcellular location: Cytoplasm. Late endosome membrane, Peripheral membrane protein. Nucleus. Also known as: VPS37A, Hepatocellular carcinoma-related protein 1.
UniProt Q8NEZ2
Application Notes IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user.
Restrictions For Research Use only
Format Lyophilized
Storage -20 °C
Xu, Liang, Wang et al.: "HCRP1, a novel gene that is downregulated in hepatocellular carcinoma, encodes a growth-inhibitory protein." in: Biochemical and biophysical research communications, Vol. 311, Issue 4, pp. 1057-66, 2003 (PubMed).

Ota, Suzuki, Nishikawa et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003 (PubMed).

Stuchell, Garrus, Müller et al.: "The human endosomal sorting complex required for transport (ESCRT-I) and its role in HIV-1 budding." in: The Journal of biological chemistry, Vol. 279, Issue 34, pp. 36059-71, 2004 (PubMed).

Bache, Slagsvold, Cabezas et al.: "The growth-regulatory protein HCRP1/hVps37A is a subunit of mammalian ESCRT-I and mediates receptor down-regulation." in: Molecular biology of the cell, Vol. 15, Issue 9, pp. 4337-46, 2004 (PubMed).

Dephoure, Zhou, Villén et al.: "A quantitative atlas of mitotic phosphorylation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 31, pp. 10762-7, 2008 (PubMed).

Alternatives for antigen "Vacuolar Protein Sorting 37 Homolog A (S. Cerevisiae) (VPS37A)", type "Antibodies"
Hosts (12)
Reactivities (11), (6), (6), (1), (1), (1)
Applications (12), (7), (6), (3), (2), (2), (1)
Conjugates (2)
Epitopes (2)
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