SNF8 antibody (Internal Region)

Catalog No. ABIN351333

Product Details anti-SNF8 Antibody

Target: SNF8 (Vacuolar-sorting Protein SNF8 (SNF8))

Binding Specificity: Internal Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNF8 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificity: Specific for SNF8.

Cross-Reactivity: Human, Mouse, Rat

Cross-Reactivity (Details): Other species not yet tested.

Purification: IgG

Immunogen: A synthetic peptide from the internal region of human SNF8 conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in rat, mouse and xenopus.

Isotype: IgG

Application Details

Application Notes: IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.

Handling Advice: Avoid freeze and thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date: 12 months

Target Details for SNF8

Target: SNF8 (Vacuolar-sorting Protein SNF8 (SNF8))

Alternative Name: SNF8 (SNF8 Products)

Synonyms: d11moh34 antibody, vps22 antibody, Dot3 antibody, EAP30 antibody, VPS22 antibody, D11moh34 antibody, RGD1310144 antibody, D11Moh34 antibody, D11MOH34 antibody, zgc:101578 antibody, SNF8, ESCRT-II complex subunit antibody, eap30 subunit of ell complex, putative antibody, EAP30 subunit of ELL complex antibody, SNF8, ESCRT-II complex subunit S homeolog antibody, SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae) antibody, snf8 antibody, TA17290 antibody, TVAG_107410 antibody, Bm1_05145 antibody, SNF8 antibody, Snf8 antibody, snf8.S antibody

Background: FUNCTION: Component of the ESCRT-II complex, which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. The ESCRT-II complex may also play a role in transcription regulation by participating in derepression of transcription by RNA polymerase II, possibly via its interaction with ELL. SUBCELLULAR LOCATION: Cytoplasm. Nucleus.,Vesicle Protein Sorting,EAP30, ELL-associated protein of 30 kDa, ESCRT-II complex subunit VPS22

UniProt: Q96H20