Vacuolar Protein Sorting 26 Homolog A (S. Pombe) (VPS26A) (Internal Region) antibody

Details for Product No. ABIN351347
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Antigen
Synonyms VPS26A, DKFZp459G2011, HB58, Hbeta58, PEP8A, VPS26, Vps26, AA407240, MNC6.7, MNC6_7, vacuolar protein sorting 26A
Epitope
Internal Region
(9), (5), (2), (1), (1), (1), (1), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Human
(29), (5), (5), (1), (1)
Host
Rabbit
(21), (6), (1), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(28), (15), (6), (3), (2), (1)
Pubmed 2 references available
Quantity 100 µL
Options
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Catalog No. ABIN351347
454.67 $
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Immunogen A synthetic peptide from the internal region of human VPS26 conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in rat and mouse.
Specificity Specific for VPS26A.
Purification Whole serum
Alternative Name VPS26
Background Function: Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA).
Subcellular location: Cytoplasm. Endosome membrane, Peripheral membrane protein. Also known as: Vacuolar protein sorting-associated protein 26A, VPS26, VPS26, VP26A.
Research Area Signaling
Application Notes A dilution of 1 : 300 to 1 : 2000 is recommended.
The optimal dilution should be determined by the end user.
Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date 12 months
Supplier Images
anti-Vacuolar Protein Sorting 26 Homolog A (S. Pombe) (VPS26A) (Internal Region) antibody WB on rat brain lysate using Rabbit antibody to internal region of Vesicle protein sorting 26A (VPS26, VPS26A): whole serum (ABIN351347) at 1 : 1000 dilution. Pre-absorption of the antibody with the immunising peptide completely abolishes the detected band.
General Lee, Radice, Perkins et al.: "Identification and characterization of a novel, evolutionarily conserved gene disrupted by the murine H beta 58 embryonic lethal transgene insertion." in: Development (Cambridge, England), Vol. 115, Issue 1, pp. 277-88, 1992 (PubMed).

Carninci, Kasukawa, Katayama et al.: "The transcriptional landscape of the mammalian genome." in: Science (New York, N.Y.), Vol. 309, Issue 5740, pp. 1559-63, 2005 (PubMed).

Validation Images
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