VAMP1 antibody (AA 2-35)

Catalog No. ABIN351355

Product Details anti-VAMP1 Antibody

Target: VAMP1 (Vesicle-Associated Membrane Protein 1 (Synaptobrevin 1) (VAMP1))

Binding Specificity: AA 2-35

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VAMP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificity: Specific for VAMP1.

Cross-Reactivity: Mouse, Rat

Cross-Reactivity (Details): Other species not yet tested.

Purification: IgG

Immunogen: A synthetic peptide from AA 2-35 of mouse VAMP-1 conjugated to an immunogenic carrier protein was used as the antigen.

Isotype: IgG

Application Details

Application Notes: IHC, WB. A working concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.

Handling Advice: Avoid freeze and thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date: 12 months

Target Details for VAMP1

Target: VAMP1 (Vesicle-Associated Membrane Protein 1 (Synaptobrevin 1) (VAMP1))

Alternative Name: VAMP-1 (VAMP1 Products)

Synonyms: SYB1 antibody, VAMP-1 antibody, Syb1 antibody, zgc:73378 antibody, wu:fj59a03 antibody, Syb-1 antibody, lew antibody, VAMP1 antibody, syb1 antibody, vamp-1 antibody, An12g07570 antibody, vesicle associated membrane protein 1 antibody, vesicle-associated membrane protein 1 antibody, vesicle-associated membrane protein 1 (synaptobrevin 1) antibody, vesicle associated membrane protein 1 L homeolog antibody, synaptobrevin 1 antibody, zgc:92912 antibody, VAMP1 antibody, Vamp1 antibody, vamp1 antibody, vamp1.L antibody, LOC100224955 antibody, ANI_1_906104 antibody, zgc:92912 antibody

Background: FUNCTION: Involved in the targeting and/or fusion of transport vesicles to their target membrane. SUBUNIT: Interacts with VAPA and VAPB. SUBCELLULAR LOCATION: Isoform 1: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane, Single-pass type IV membrane protein. Cell junction, synapse, synaptosome. SUBCELLULAR LOCATION: Isoform 2: Cytoplasmic vesicle membrane, Single-pass type IV membrane protein. Note: Isoforms 2 and 3 are found in perinuclear as well as peripheral punctate structures in osteoblasts. SUBCELLULAR LOCATION: Isoform 3: Mitochondrion outer membrane, Single-pass type IV membrane protein. Note=Isoforms 2 and 3 are found in perinuclear as well as peripheral punctate structures in osteoblasts. TISSUE SPECIFICITY: Expressed in brain and spleen (at protein level). Isoform 1 expressed at very high level in brain. Even higher level found in spinal cord. Isoform 3 expressed in kidney, spleen and liver. Isoforms 2 and 3 expressed in osteoblasts of trabecular bone. Also expressed in heart.,Vesicle Transport,VAMP-1, Vamp1, Synaptobrevin-1, Syb1

UniProt: Q63666