Vesicle-Associated Membrane Protein 3 (VAMP3) antibody

Details for Product No. ABIN351361
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Antigen
Synonyms ceb, VAMP-3, D130027G05Rik, CEB, zgc:73378, wu:fj59a03, zgc:86726, vamp-3
Reactivity
Mouse (Murine)
(48), (24), (20), (12), (12), (12), (12), (12)
Host
Rabbit
(37), (17), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(40), (29), (13), (10), (7), (3), (2), (1), (1), (1)
Pubmed 7 references available
Catalog no. ABIN351361
Quantity 100 µL
Price
454.67 $   Plus shipping costs $45.00
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  • +1 404 474 4654
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Immunogen A synthetic peptide from human VAMP3 conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in rat and mouse.
Specificity Specific for MOR258-2.
Purification whole serum
Alternative Name Vesicle-associated membrane protein 3 (VAMP3 Synaptobrevin-3, Cellubrevin)
Background Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Because of its high homology to other known VAMPs, its broad tissue distribution, and its subcellular localization, the protein encoded by this gene was shown to be the human equivalent of the rodent cellubrevin. In platelets the protein resides on a compartment that is not mobilized to the plasma membrane on calcium or thrombin stimulation.
Function: Trafficking protein from a constitutively recycling pathway.
Subcellular location: Membrane, Single-pass type IV membrane protein. Cell junction, synapse, synaptosome. Also known as: VAMP-3, VAMP3, Synaptobrevin-3, Cellubrevin, SYB3, CEB.
UniProt Q8VGB1
Application Notes A dilution of 1 : 300 to 1 : 2000 is recommended.
The optimal dilution should be determined by the end user.
Not yet tested in other applications.
Restrictions For Research Use only
Format Liquid
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage -20 °C
Storage Comment Maintain the reconstituted antibodies frozen at -20 °C for long term storage and refrigerated at 2-8 °C for a shorter term.
Expiry Date 12 months
General McMahon, Ushkaryov, Edelmann et al.: "Cellubrevin is a ubiquitous tetanus-toxin substrate homologous to a putative synaptic vesicle fusion protein." in: Nature, Vol. 364, Issue 6435, pp. 346-9, 1993 (PubMed).

Bernstein, Whiteheart: "Identification of a cellubrevin/vesicle associated membrane protein 3 homologue in human platelets." in: Blood, Vol. 93, Issue 2, pp. 571-9, 1999 (PubMed).

Yang, Mora, Ryder et al.: "VAMP3 null mice display normal constitutive, insulin- and exercise-regulated vesicle trafficking." in: Molecular and cellular biology, Vol. 21, Issue 5, pp. 1573-80, 2001 (PubMed).

Gevaert, Goethals, Martens et al.: "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides." in: Nature biotechnology, Vol. 21, Issue 5, pp. 566-9, 2003 (PubMed).

Carninci, Kasukawa, Katayama et al.: "The transcriptional landscape of the mammalian genome...." in: Science (New York, N.Y.), Vol. 309, Issue 5740, pp. 1559-63, 2005 (PubMed).

Gregory, Barlow, McLay et al.: "The DNA sequence and biological annotation of human chromosome 1...." in: Nature, Vol. 441, Issue 7091, pp. 315-21, 2006 (PubMed).

Matsuoka, Ballif, Smogorzewska et al.: "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage." in: Science (New York, N.Y.), Vol. 316, Issue 5828, pp. 1160-6, 2007 (PubMed).

Hosts (37), (17), (1)
Reactivities (48), (24), (20), (12), (12), (12), (12), (12)
Applications (40), (29), (13), (10), (7), (3), (2), (1), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (15), (5), (3), (2), (2), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
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