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Details for Product No. ABIN351384

Solute Carrier Family 17 (Sodium-Dependent Inorganic Phosphate Cotransporter), Member 8 (SLC17A8) (C-Term) antibody

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Antigen
Synonyms Vglut3, BC042593, DFNA25, VGLUT3, vglut3, si:ch211-264e16.4
Epitope
»Alternatives C-Term
Reactivity
»Alternatives Mouse (Murine)
Host
»Alternatives Rabbit
Clonality Polyclonal
Application
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 5 references available
Catalog no. ABIN351384
Quantity 100 µL
Price
454.67 $   Plus shipping costs $45.00
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Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide from the c-terminal region of mouse VGLUT3 conjugated to an immunogenic carrier protein was used as the immunogen.
Specificity Appears to be specific for VGLUT3.
Purity whole serum
Alternative Name VGluT3 (Vesicular glutamate transporter 3)
Background Function: Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate.
Subcellular location: Cytoplasmic vesicle › secretory vesicle › synaptic vesicle membrane. Membrane, Multi-pass membrane proteinPotential. Cell junction › synapse › synaptosome.
Tissue specificity: Expressed in brain, kidney and liver. Expressed within the amygdala, brainstem, cerberal cortex, dorsal root ganglia, dorsal spinal cord, hippocampus, hypothalamus, retina, striatum and ventral spinal cord. Expressed within neurons of the caudate-putamen,olfactory tubercle, nucleus accumbens, hippocampus, interpeduncular nucleus and dorsal and medial raphe nuclei. Expressed in inner hair cells of the ear. Expressed at synaptic terminals within the lateral superior olive (LSO), a nucleus of the mammalian sound localization system, and in the medial nucleus of the trapezoid body (MNTB), which provides inhibitory input to the LSO. Also known as: Vesicular glutamate transporter 3, Solute carrier family 17 member 8.
UniProt Q8BFU8
Application Notes IHC, WB. A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Storage -20 °C
Schaefer, Varoqui, Defamie et al.: "Molecular cloning and functional identification of mouse vesicular glutamate transporter 3 and its expression in subsets of novel excitatory neurons." in: The Journal of biological chemistry, Vol. 277, Issue 52, pp. 50734-48, 2002 (PubMed).

Mackenzie, Illing, Morris et al.: "Analysis of a vesicular glutamate transporter (VGLUT2) supports a cell-leakage mode in addition to vesicular packaging." in: Neurochemical research, Vol. 33, Issue 2, pp. 238-47, 2008 (PubMed).

Seal, Akil, Yi et al.: "Sensorineural deafness and seizures in mice lacking vesicular glutamate transporter 3." in: Neuron, Vol. 57, Issue 2, pp. 263-75, 2008 (PubMed).

Gras, Amilhon, Lepicard et al.: "The vesicular glutamate transporter VGLUT3 synergizes striatal acetylcholine tone." in: Nature neuroscience, Vol. 11, Issue 3, pp. 292-300, 2008 (PubMed).

Ruel, Emery, Nouvian et al.: "Impairment of SLC17A8 encoding vesicular glutamate transporter-3, VGLUT3, underlies nonsyndromic deafness DFNA25 and inner hair cell dysfunction in null mice." in: American journal of human genetics, Vol. 83, Issue 2, pp. 278-92, 2008 (PubMed).

Alternatives for antigen "Solute Carrier Family 17 (Sodium-Dependent Inorganic Phosphate Cotransporter), Member 8 (SLC17A8)", type "Antibodies"
Hosts (13), (4), (2), (1)
Reactivities (11), (6), (2)
Applications (17), (12), (5), (3), (2), (2), (2), (2), (2), (1)
Epitopes (9), (3), (2), (2), (1)
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