SLC17A8 antibody (Internal Region)

Catalog No. ABIN351387

Product Details anti-SLC17A8 Antibody

Target: SLC17A8 (Solute Carrier Family 17 (Sodium-Dependent Inorganic Phosphate Cotransporter), Member 8 (SLC17A8))

Binding Specificity: Internal Region

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC17A8 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificity: Specific for VGLUT3.

Immunogen: A synthetic peptide from the internal region of rat VGLUT3 conjugated to an immunogenic carrier protein was used as the antigen.

Isotype: IgG

Application Details

Application Notes: A concentration of 10-50 µg/ml is recommended.
The optimal concentration should be determined by the end user.
Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.

Handling Advice: Avoid freeze and thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date: 12 months

Target Details for SLC17A8

Target: SLC17A8 (Solute Carrier Family 17 (Sodium-Dependent Inorganic Phosphate Cotransporter), Member 8 (SLC17A8))

Alternative Name: VGluT3 (SLC17A8 Products)

Synonyms: vglut3 antibody, si:ch211-264e16.4 antibody, BC042593 antibody, Vglut3 antibody, DFNA25 antibody, VGLUT3 antibody, solute carrier family 17 member 8 antibody, solute carrier family 17 (vesicular glutamate transporter), member 8 antibody, vesicular glutamate transporter 3 antibody, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8 antibody, SLC17A8 antibody, slc17a8 antibody, Tsp_11966 antibody, Tsp_00373 antibody, Slc17a8 antibody

Background: Function: Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate.
Subcellular location: Cytoplasmic vesicle › secretory vesicle › synaptic vesicle membrane. Membrane, Multi-pass membrane proteinPotential. Cell junction › synapse › synaptosome.
Tissue specificity: Expressed in brain, kidney and liver. Expressed within the amygdala, brainstem, cerberal cortex, dorsal root ganglia, dorsal spinal cord, hippocampus, hypothalamus, retina, striatum and ventral spinal cord. Expressed within neurons of the caudate-putamen,olfactory tubercle, nucleus accumbens, hippocampus, interpeduncular nucleus and dorsal and medial raphe nuclei. Expressed in inner hair cells of the ear. Expressed at synaptic terminals within the lateral superior olive (LSO), a nucleus of the mammalian sound localization system, and in the medial nucleus of the trapezoid body (MNTB), which provides inhibitory input to the LSO. Also known as: Vesicular glutamate transporter 3, Solute carrier family 17 member 8.

Pathways: Sensory Perception of Sound, Dicarboxylic Acid Transport