Vomeronasal Type-1 Receptor 5 (VN1R5) antibody

Antigen: Vomeronasal Type-1 Receptor 5 (VN1R5)

Synonyms: V1RL5, V1rc18

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Catalog no.: ABIN351392

Additional Information

Alternative name: vomeronasal 1 receptor 5 (VN1R5, V1RL5)

Swiss-Prot: Q7Z5H4

Immunogen: A synthetic peptide as a part of human vomeronasal 1 receptor 5 (VN1R5, V1RL5) conjugated to immunogenic carrier protein was used as the immunogen.

Format: Lyophilized

Description: FUNCTION: Putative pheromone receptor. SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. POLYMORPHISM: There is an allele VN1R5*2 with a truncating mutation in position 46. It was found with a frequency of about 32%. MISCELLANEOUS: The chimpanzee and orangutan orthologous proteins do not exist, their genes are pseudogenes. Useful Links <||a href="http://bioportal.weizmann.ac.il/HORDE/links.html"> The Humanolfactory Data Exploratorium: HORDE <||/a> <||a href="http://senselab.med.yale.edu/senselab/ordb/">olfactory Receptor Data Base: ORDB <||/a> <||a href="http://www.enzim.hu/hmmtop1.1/server/submit.html">transmembrane Analysis: TM analysis<||/a> Also known as:vomeronasal type-1 receptor 5, V1r-like receptor 5, hGPCR26, VN1R5, V1RL5.

Specificity: Appears to be specific for VN1R5.

Application Details

Application Notes: IHC, WB. A dilution of 1 : 300 to 1 : 3000 is recommended. The optimal dilution should be determined by the end user.

Purity: whole serum

Storage: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Restrictions: For Research Use only

Publications

Publications: Takeda, Kadowaki, Haga et al.: "Identification of G protein-coupled receptor genes from the human genome sequence." in: FEBS letters, Vol. 520, Issue 1-3, pp. 97-101, 2002 (PubMed).

Rodriguez, Mombaerts: "Novel human vomeronasal receptor-like genes reveal species-specific families." in: Current biology : CB, Vol. 12, Issue 12, pp. R409-11, 2002 (PubMed).

Zhang, Webb: "Evolutionary deterioration of the vomeronasal pheromone transduction pathway in catarrhine primates." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 14, pp. 8337-41, 2003 (PubMed).