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Details for Product No. ABIN351412

VP33B (Vesicle Protein Sorting Associated Protein 33B) (C-Term) antibody

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Antigen
Epitope
C-Term
Reactivity
Human
Host
Rabbit
Clonality Polyclonal
Application
Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 3 references available
Catalog no. ABIN351412
Quantity 100 µL
Price
454.67 $   Plus shipping costs $45.00
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Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide from the c-terminal of rat VP33B (Vesicle protein sorting associated protein 33B) conjugated to an immunogenic carrier protein was used as the antigen. The antigen shares 91% identity with rat's and human's.
Specificity Specific for P2RY11.
Purity whole serum
Background Function: May play a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes.
Subcellular location: Late endosome membrane, Peripheral membrane protein, Cytoplasmic side. Lysosome membrane, Peripheral membrane protein, Cytoplasmic side. Note: Cytoplasmic, peripheral membrane protein associated with late endosomes/lysosomes.
Tissue specificity: Ubiquitous. Also known as: Vesicle protein sorting associated protein 33B, Vacuolar protein sorting-associated protein 33B.
UniProt Q96G91
Application Notes A dilution of 1: 200 to 1: 1000 is recommended.
The optimal dilution should be determined by the end user.
Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage -20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20 °C for long term storage and refrigerated at 2-8 °C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability.
Expiry Date 12 months
Pevsner, Hsu, Hyde et al.: "Mammalian homologues of yeast vacuolar protein sorting (vps) genes implicated in Golgi-to-lysosome trafficking." in: Gene, Vol. 183, Issue 1-2, pp. 7-14, 1997 (PubMed).

Ota, Suzuki, Nishikawa et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003 (PubMed).

Gissen, Johnson, Morgan et al.: "Mutations in VPS33B, encoding a regulator of SNARE-dependent membrane fusion, cause arthrogryposis-renal dysfunction-cholestasis (ARC) syndrome." in: Nature genetics, Vol. 36, Issue 4, pp. 400-4, 2004 (PubMed).

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