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Details for Product No. ABIN351412

VP33B (Vesicle Protein Sorting Associated Protein 33B) (C-Term) antibody

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Antigen
Epitope
C-Term
Reactivity
Rat (Rattus), Human
Host
Rabbit
Clonality Polyclonal
Application
Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 3 references available
Catalog no. ABIN351412
Quantity 100 µL
Price
454.67 $   Plus shipping costs $45.00
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Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide from the c-terminal of rat VP33B (Vesicle protein sorting associated protein 33B) conjugated to an immunogenic carrier protein was used as the immunogen. The antigen shares 91% identity with rat's and human's.
Specificity Appears to be specific for VP33B.
Purity whole serum
Background Function: May play a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes.
Subcellular location: Late endosome membrane, Peripheral membrane protein, Cytoplasmic side. Lysosome membrane, Peripheral membrane protein, Cytoplasmic side. Note: Cytoplasmic, peripheral membrane protein associated with late endosomes/lysosomes.
Tissue specificity: Ubiquitous. Also known as: Vesicle protein sorting associated protein 33B, Vacuolar protein sorting-associated protein 33B.
UniProt Q63616
Application Notes IHC, WB (confirmed by recombinant protein). A dilution of 1: 200 to 1: 1000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Storage -20 °C
Pevsner, Hsu, Hyde et al.: "Mammalian homologues of yeast vacuolar protein sorting (vps) genes implicated in Golgi-to-lysosome trafficking." in: Gene, Vol. 183, Issue 1-2, pp. 7-14, 1997 (PubMed).

Ota, Suzuki, Nishikawa et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003 (PubMed).

Gissen, Johnson, Morgan et al.: "Mutations in VPS33B, encoding a regulator of SNARE-dependent membrane fusion, cause arthrogryposis-renal dysfunction-cholestasis (ARC) syndrome." in: Nature genetics, Vol. 36, Issue 4, pp. 400-4, 2004 (PubMed).

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