You are viewing an incomplete version of our website. Please click to reload the website as full version.

Prostaglandin D2 Receptor 2 (PTGDR2) antibody

Details for Product No. ABIN351421, Supplier: Login to see New
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Synonyms CRTH2, GPR44, Crth2, Grp45, Ptgdr2, CD294, DL1R, DP2, Gpr44
(105), (36), (32), (2)
(85), (20), (2)
Clonality (Clone)
Monoclonal ()
(3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
ELISA, Western Blotting (WB)
(52), (42), (35), (30), (16), (11), (9), (6), (4), (2), (2), (2), (1)
Pubmed 2 references available
Supplier Login to see New
Catalog number from supplier Login to see New
Quantity 50 μg
Shipping to United States ( )
Availability Will be delivered in 9 to 11 Business Days
Immunogen Partial peptide of Human GPR44
Clone 8F2
Isotype IgG1, kappa chain
Purification Protein G Affinity Purified
Alternative Name G protein-coupled receptor 44 (GPR44, CD294) (PTGDR2 Antibody Abstract)
Background CRTH2, also known as GPR44, DP2, CD294, is a member of G protein-coupled receptor and activated by prostaglandin D2 (PGD2) and its PGD2 metabolites. CRTH2 is predominantly expressed on Th2-type T cells, eosinophils and basophils and mediates their chemotaxis to PGD2. CRTH2 mediates the respiratory burst and degranulation of eosinophils, induces the production of proinflammatory cytokines in Th2 cells, and enhances the release of histamine from basophils. PGD2- CRTH2 system also may play important roles in the development of chronic allergic skin inflammation.
Gene ID 11251
Research Area Inflammation
Application Notes Recommended Dilutions: Western Blotting 20ug/ml, ELISA 1ug/ml
Restrictions For Research Use only
Concentration 0.25 mg/ml
Buffer PBS [containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat]
Preservative ProClin
Storage -20 °C
Background publications Satoh, Moroi, Aritake et al.: "Prostaglandin D2 plays an essential role in chronic allergic inflammation of the skin via CRTH2 receptor." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 177, Issue 4, pp. 2621-9, 2006 (PubMed).

Iwasaki, Nagata, Takano et al.: "Association of a new-type prostaglandin D2 receptor CRTH2 with circulating T helper 2 cells in patients with atopic dermatitis." in: The Journal of investigative dermatology, Vol. 119, Issue 3, pp. 609-16, 2002 (PubMed).

Catalog No. ABIN351421
Plus shipping costs $45.00

Order hotline:

  • +1 877 302 8632
  • +1 888 205 9894 (TF)