STEAP1 (C-Term) antibody

Antigen: STEAP1 (C-Term)

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Catalog no.: ABIN351550

Additional Information

Swiss-Prot: Q9UHE8

Immunogen: Synthetic peptide, An 18 amino acid peptide located near the c-terminal region of human STEAP1.

Description: Gene: STEAP1, Standard Gene Symbol: STEAP1, Synonyms: STEAP1, MGC19484, PRSS24, Six transmembrane epithelial antigen of the prostate, STEAP

Specificity: Recognizes STEAP1 (six transmembrane epithelial antigen of the prostate), a 39kD protein which is a member of a family of cell surface serpentine transmembrane antigens of the prostate. STEAP1 is predominantly expressed in human prostate and is up-regulated in several cancer lines including prostate, ovarian, cervical, breast, testicular, bladder, colon and Ewing sarcoma. It is significantly expressed at cell-cell junctions and has been shown to be a target of human CD8 T cells. This indicates that it could be used as a potential target for cancer immunotherapy. This antibody does not cross-react with other STEAP-proteins Predicted Reactivities: Mouse (Murine),Rat (Rattus).

Application Details

Application Notes: IHC-P (5 µg/ml), WB (1 - 2 µg/ml)

Concentration: 1 mg/ml

Purification: Affinity Chromatography

Buffer: PBS, 0.02% sodium azide.

Storage: Long term: -20°C, Short term: +4°C

Restrictions: For Research Use only

Images

Human Lung, Bronchiole (formalin-fixed, paraffin-embedded) stained with STEAP1 antibody ABIN351550 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen.