FGFR1 (pTyr654,pTyr653) antibody

Antigen: FGFR1 (pTyr654,pTyr653)

Clonality: Monoclonal

Host: Mouse

Reactivity: Human

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Catalog no.: ABIN351555

Additional Information

Swiss-Prot: P11362

Immunogen: Synthetic peptide, Synthetic phosphopeptide corresponding to residues surrounding Tyr653/654 of human FGF receptor-1 (KLH coupled). The corresponding sequences are identical in FGF receptor-2, -3 and -4.

Isotype: IgG2b  (Matching secondary antibodies)

Description: Gene: FGFR1, Standard Gene Symbol: FGFR1, Family: Protein Kinase, Subfamily: FGF Receptor, Synonyms: FGFR1, Basic fibroblast growth factor receptor, BFGF receptor, BFGF-R, bFGF-R-1, BFGFR, CD331, CEK, Cek1, FGF receptor 1, Fgf-flg, FGFBR, FGFR-1, Fibroblast growth factor receptor 1, Fibroblast growth factor receptor flg, FLG, FLJ99988, FLT-2, FLT2, Fms-related tyrosine kinase-2, H3, HBGF receptor, HBGFR, Heparin-binding growth factor receptor, KAL2, N-SAM, OGD

Specificity: Detects overexpressed levels of Tyr653/654 phosphorylated FGF receptors. Slightly cross-reactivity with activated PDGF and insulin/IGF-I receptors. Does not cross-react with other tyrosine-phosphorylated proteins.

Application Details

Application Notes: IHC-P (1:50), WB (1:1000)

Purification: Ascites

Buffer: 10 mM sodium HEPES, pH 7.5, 150 mM sodium chloride, 0.1 mg/ml BSA, 50% glycerol.

Storage: Long term: -20°C, Short term: +4°C

Restrictions: For Research Use only

Images

Human Pancreas (formalin-fixed, paraffin-embedded) stained with FGFR1 antibody ABIN351555 at 1:50 followed by biotinylated anti-mouse IgG secondary antibody ABIN481714, alkaline phosphatase-streptavidin and chromogen.