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CD5 antibody (FITC)

CD5 Reactivity: Mouse FACS, WB, IP, IHC (fro), Func Host: Rat Monoclonal 4H8E6 FITC
Catalog No. ABIN356202
  • Target See all CD5 Antibodies
    CD5
    Reactivity
    • 222
    • 89
    • 58
    • 27
    • 22
    • 16
    • 15
    • 15
    • 13
    • 12
    • 11
    • 10
    • 5
    • 2
    • 1
    • 1
    • 1
    Mouse
    Host
    • 167
    • 81
    • 55
    • 1
    Rat
    Clonality
    • 232
    • 70
    Monoclonal
    Conjugate
    • 110
    • 37
    • 32
    • 28
    • 13
    • 8
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD5 antibody is conjugated to FITC
    Application
    • 235
    • 108
    • 68
    • 67
    • 64
    • 53
    • 30
    • 28
    • 22
    • 18
    • 13
    • 13
    • 11
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)
    Specificity
    This antibody is specific to CD5/Lyt-1 (Mr. 67 kDa)
    Characteristics
    Synonyms: Lymphocyte antigen T1/Leu-1, LEU1, T-cell surface glycoprotein CD5
    Clone
    4H8E6
    Isotype
    IgG2a
    Top Product
    Discover our top product CD5 Primary Antibody
  • Application Notes
    Flow Cytometry: Identification and enumeration of CD5+ cells (< / = 1 μg/10^6 cells). (Ref.15)Immunoprecipitation. (Ref.15)Immunohistochemistry on Frozen Sections. (Ref.15)T Cell Activation. (Ref.15)Western blotting. (Ref.15)
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    PBS containing 0.09 % Sodium Azide as preservative.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    Expiry Date
    12 months
  • Target
    CD5
    Alternative Name
    CD5 (CD5 Products)
    Synonyms
    CD5 antibody, Ly-1 antibody, Ly-12 antibody, Ly-A antibody, Lyt-1 antibody, LEU1 antibody, T1 antibody, CD5 molecule antibody, CD5 antigen antibody, CD5 molecule like antibody, Cd5 molecule antibody, CD5 antibody, Cd5 antibody, CD5L antibody
    Background
    CD5/Lyt-1 antigen is a monomeric type I transmembrane glycoprotein expressed on thymocytes, T lymphocytes, and a subset of B lymphocytes, but not on natural killer (NK) cells. (Ref.1-3) It has been identified as the major ligand of the B-cell antigen CD72. (Ref.4,5) The frequency of CD5+ B cells exhibits strain-dependent variation, and the phenotypic, anatomical, functional, developmental, and pathological characteristics of the CD5+ B cells suggest that they may represent a distinct lineage, known as B-1 cells (reviewed in Ref.6). Binding of CD5 on the T cell surface can augment alloantigen- or mitogen-induced lymphocyte proliferation and induces increased cytosolic free calcium, IL-2 secretion, and IL-2R expression. (Ref.7-12) It has been proposed that CD5 negatively regulates signal transduction mediated by the T-cell and B-cell receptors. (Ref.13,14)Synonyms: CD5, LEU1, Lymphocyte antigen T1/Leu-1, T-cell surface glycoprotein CD5
    Gene ID
    12507
    UniProt
    P13379
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