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S100A1 antibody (FITC)

S100A1 Reactivity: Human, Mouse, Rat, Cow IF, FACS, IHC (fro) Host: Mouse Monoclonal S100217 FITC
Catalog No. ABIN356321
  • Target See all S100A1 Antibodies
    S100A1 (S100 Calcium Binding Protein A1 (S100A1))
    Reactivity
    • 87
    • 39
    • 32
    • 25
    • 13
    • 13
    • 5
    • 3
    Human, Mouse, Rat, Cow
    Host
    • 72
    • 23
    • 3
    Mouse
    Clonality
    • 64
    • 35
    Monoclonal
    Conjugate
    • 49
    • 10
    • 8
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This S100A1 antibody is conjugated to FITC
    Application
    • 62
    • 40
    • 37
    • 20
    • 18
    • 11
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificity
    This antibody stains schwannoma, ependymomas, astrogliomas, almost all benign and malignant melanoma and their metasis.
    Cellular Localization: Cytoplasmic.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human, Monkey, Bovine, Rat and Mouse
    Characteristics
    Synonyms: S100 Calcium binding protein, S-100 protein, S100A, S100B, S-100 protein alpha chain,S-100 protein beta chain, Astrocyte Marker, S-100 protein alpha subunit, S-100 proteinbeta subunit, S100 Alpha, S100 Beta
    Purification
    Protein A Chromatography.
    Immunogen
    Purified bovine S100 protein. Remarks: Molecular weight of antigen: ~22 kDa.
    Clone
    S100217
    Isotype
    IgG1
    Top Product
    Discover our top product S100A1 Primary Antibody
  • Application Notes
    Suitable for Immunohistochemistry and Immunocytochemistry (Frozen or Formalin-FixedParaffin-Embedded (FFPE) tissue sections and cell smears)For IHC dilute concentared antibody at 1/50-1/100, use streptavidinapprox. biotin system orpolymer system, incubate 30 minutes at room temperature.
    Restrictions
    For Research Use only
  • Concentration
    0.2 mg/mL
    Buffer
    PBS, pH 7.4, 0.05 % Sodium Azide, 1 % BSA
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.
    Shelf life: One year from despatch.
    Expiry Date
    12 months
  • Target
    S100A1 (S100 Calcium Binding Protein A1 (S100A1))
    Alternative Name
    S100A1 (S100A1 Products)
    Synonyms
    S100 antibody, S100-alpha antibody, S100A antibody, S100A1 antibody, DKFZp468K0511 antibody, AI266795 antibody, S100a antibody, S100 calcium binding protein A1 antibody, S100A1 antibody, S100a1 antibody, s100a1 antibody
    Background
    S100 protein is a type of low molecular weight protein found in vertebrates characterized by two calcium binding sites of the helix-loop-helix ("EF-hand type") conformation. There are at least 21 different types of S100 proteins. The name is derived from the fact that the protein is 100 % Soluble in ammonium sulfate at neutral pH . Most S100 proteins are homodimeric, consisting of two identical polypeptides held together by non-covalent bonds. S100A is composed of an alpha and beta chain whereas S100B is composed of two beta chains. Although S100 proteins are structurally similar to calmodulin, they differ in that they are cell-specific, expressed in particular cells at different levels depending on environmental factors. To contrast, calmodulin is a ubiquitous and universal intracellular Ca++ receptor widely expressed in many cells.S-100 is normally present in cells derived from the neural crest (Schwann cells, melanocytes, and glia cells), chondrocyte, adipocytes, myoepithelial cells, macrophages, Langerhans cells, dendritic cells, and keratinocytes. It may be present in some breast epithelial cells.Synonyms: Astrocyte Marker, S-100 protein, S-100 protein alpha chain, S-100 protein alpha subunit, S-100 protein beta chain, S-100 protein beta subunit, S100 Alpha, S100 Beta, S100 Calcium binding protein, S100A, S100B
    Gene ID
    528735
    UniProt
    P02639
    Pathways
    Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades, S100 Proteins
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