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ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4) (C-Term) antibody

Antigen

ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4)
Synonyms
ADMP-1, ADAMTS-2, ADAMTS-4, KIAA0688, KIAA0366, ADAM-TS4, mKIAA0688, 3830423K05, ADAMTS4, DKFZp469J0817, AAC2, PNAT, NPI, PCINP, PCPNI, hPCPNI, ADAM-TS2, ADAMTS-3, TTP, VWFCP, C9orf8, vWF-CP, FLJ42993 ... show more
Epitope
Alternatives

C-Term
Clonality Polyclonal
Host
Alternatives

Rabbit
Reactivity
Alternatives

Human
Application
Alternatives Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Catalog no. ABIN356434
Quantity 50 µg  (1.0 mg/ml)  (Variants)
Price 390.00 $   Plus shipping costs $35.00
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Additional Information
Application Details Alternatives Secondary Antibodies Variants back to top

Characteristics Synonyms: ADAMTS-4, ADAM-TS4, Aggrecanase-1, ADMP1, ADMP-1, KIAA0688, A disintegrin andmetalloproteinase with thrombospondin motifs 4
Alternative name ADAMTS4
Swiss-Prot O75173
Immunogen Synthetic peptide corresponding to C-terminal domain of human ADAMTS4 - KLHconjugated. Remarks: Rat Identity: 29%Rat Similarity: 41%
Cross-Reactivity Human
Isotype IgG  (Matching secondary antibodies)
Description ADAMTS4, also known as aggrecanase-1, is a Metallopeptidase M12B type protease that isresponsible for degradation of the articular cartilage protein aggrecan and the brainextracellular matrix proteoglycan brevican. The ADAMTS4 protein contains a signalsequence, a propeptide domain, a catalytic domain, a disintegrin-like motif, and aC-terminal domain with a thrombospondin (TSP) type 1 motif. ADAMTS4 has beenimplicated in inflammatory joint diseases, and it also may be a factor in the progression ofglioma and Alzheimer's disease.
Specificity This antibody reacts with C-terminal domain of ADAMTS4. Species: Human. Others not tested.
Synonyms ADMP-1, ADAMTS-2, ADAMTS-4, KIAA0688, KIAA0366, ADAM-TS4, mKIAA0688, 3830423K05, ADAMTS4, DKFZp469J0817, AAC2, PNAT, NPI, PCINP, PCPNI, hPCPNI, ADAM-TS2, ADAMTS-3, TTP, VWFCP, C9orf8, vWF-CP, FLJ42993, MGC118899, MGC118900, DKFZp434C2322, ADMP-2, ADAMTS11, FLJ36738, ASMP-2, ADAMTS1, ADAM-TS5, AI481094, 9530092O11Rik, PWTSR, THSD2, CRISTIN1, FLJ14440, AW743315, 1810011L16Rik, 8430403M15Rik, E030027K14Rik, FLJ16042, AU015154, 4831407I23Rik, D230034E10Rik, Gm710, ADAMTS5, ADAMTS13, ADAMTS-11

Application Details
Alternatives Secondary Antibodies Variants back to top

Application Notes Immunohistochemistry on Paraffin Embedded Tissues: 20 µg/ml. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Concentration 1.0 mg/ml
Purification Aff - Purified
Buffer PBS containing 0.09% Sodium Azide as preservative.
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Restrictions For Research Use only

Alternatives
Application Details Secondary Antibodies Variants back to top

Alternatives for antigen "ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4)", type "Antibodies"
Hosts Rabbit (34), Mouse (2), Goat (1)
Reactivities Human (33), Mouse (Murine) (24), Rat (Rattus) (20), Cow (Bovine) (1), Dog (Canine) (1), Pig (Porcine) (1), Rabbit (1)
Applications Flow Cytometry (FACS) (18), Immunofluorescence (IF) (18), Western Blotting (WB) (16), ELISA (6), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (5), Immunohistochemistry (IHC) (3), Immunoprecipitation (IP) (3), Enzyme Immunoassay (EIA) (2), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), ELISA (Detection) (1), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1)
Conjugates Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
Epitopes C-Term (4)