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LHB antibody

LHB Reactivity: Human IF, IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN356493
  • Target See all LHB Antibodies
    LHB (Luteinizing Hormone beta Polypeptide (LHB))
    Reactivity
    • 56
    • 10
    • 8
    • 7
    • 1
    • 1
    • 1
    Human
    Host
    • 38
    • 31
    • 2
    • 1
    Rabbit
    Clonality
    • 39
    • 33
    Polyclonal
    Conjugate
    • 35
    • 7
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LHB antibody is un-conjugated
    Application
    • 26
    • 25
    • 14
    • 12
    • 10
    • 10
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificity
    This antibody stains both free and intact LH and is useful for the classification of pituitary adenomas and tumors of the pituitary.
    Cellular Localization: Cytoplasmic.
    Purification
    Protein A Chromatography.
    Immunogen
    LH beta.
    Isotype
    IgG
    Top Product
    Discover our top product LHB Primary Antibody
  • Application Notes
    Suitable for Immunohistochemistry and Immunocytochemistry (Frozen or Formalin-FixedParaffin-Embedded (FFPE) tissue sections and cell smears): 1/50-1/100 usingstreptavidinapprox. biotin system or polymer system. Positive Control: Human anterior pituitary.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    2.0 mg/mL
    Buffer
    10 mM PO4, 150 mM NaCl, pH 7.4 containing 0.05 % Sodium Azide as preservative and 1 % BSA as stabilizer.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    LHB (Luteinizing Hormone beta Polypeptide (LHB))
    Alternative Name
    Luteinizing Hormone beta (LSH-Beta) (LHB Products)
    Synonyms
    CGB4 antibody, LSH-B antibody, hLHB antibody, LH antibody, LH-B antibody, LSH-beta antibody, cgb4 antibody, hlhb antibody, xlhb antibody, lhb-A antibody, lsh-b antibody, LH/CG-beta antibody, LHB antibody, LSH-B/CG-B antibody, Lutropin beta chain antibody, lhb1 antibody, lhbeta1 antibody, zgc:92312 antibody, lhb antibody, luteinizing hormone beta polypeptide antibody, luteinizing hormone beta antibody, lutropin subunit beta-like antibody, luteinizing hormone, beta polypeptide antibody, luteinizing hormone beta polypeptide L homeolog antibody, LHB antibody, Lhb antibody, lhb antibody, LOC106838274 antibody, lhb.L antibody
    Background
    Luteinizing Hormone (LH) is a tropic hormone which modulates the secretory activity of other endocrine glands. This glycoprotein hormone is produced in the anterior hypophysis of the pituitary gland. In the female an acute rise of LH the LH surge - triggers ovulation. In the male, where LH had also been called Interstitial Cell Stimulating Hormone (ICSH), it stimulates Leydig cell production of testosterone. The alpha subunits of LH, FSH, TSH, and hCG are identical, and contain 92 amino acids, the beta subunit vary. LH has a beta subunit of 121 amino acids (LHB) that confers its specific biologic action. and is responsible for interaction with the LH receptor.Synonyms: LH-B, LHB, LSH-beta, Luteinizing hormone subunit beta, Lutropin beta chain, Lutropin subunit beta
    Gene ID
    3972
    NCBI Accession
    NP_000885
    UniProt
    P01229
    Pathways
    Metabolism of Steroid Hormones and Vitamin D, Peptide Hormone Metabolism, Hormone Activity, C21-Steroid Hormone Metabolic Process
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