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SOX9 antibody (N-Term)

SOX9 Reactivity: Human WB, IF, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN356879
  • Target See all SOX9 Antibodies
    SOX9 (SRY (Sex Determining Region Y)-Box 9 (SOX9))
    Binding Specificity
    • 16
    • 16
    • 13
    • 10
    • 8
    • 8
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 143
    • 69
    • 51
    • 20
    • 10
    • 6
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Host
    • 122
    • 22
    • 2
    Rabbit
    Clonality
    • 107
    • 39
    Polyclonal
    Conjugate
    • 78
    • 9
    • 8
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    This SOX9 antibody is un-conjugated
    Application
    • 117
    • 67
    • 44
    • 40
    • 34
    • 27
    • 27
    • 21
    • 13
    • 10
    • 7
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects SOX9 at N-term.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human.
    Purification
    Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS, then purified by peptide affinity purification.
    Immunogen
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human SOX9.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product SOX9 Primary Antibody
  • Application Notes
    ELISA: 1/1,000. Western blot: 1/50-1/100. Immunohistochemistry. Immunofluorescence: 1/10-1/50.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) Sodium Azide as preservative.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    SOX9 (SRY (Sex Determining Region Y)-Box 9 (SOX9))
    Alternative Name
    SOX9 (SOX9 Products)
    Synonyms
    CMD1 antibody, CMPD1 antibody, SRA1 antibody, LOC100227849 antibody, 2010306G03Rik antibody, AV220920 antibody, mKIAA4243 antibody, SOX-9 antibody, cmd1 antibody, cmpd1 antibody, sox-9 antibody, sox9 antibody, sox9-a antibody, sox9-b antibody, sox9b antibody, sra1 antibody, SRY-box 9 antibody, transcription factor SOX-9 antibody, SRY (sex determining region Y)-box 9 antibody, SRY box 9 antibody, SRY-box 9 L homeolog antibody, SOX9 antibody, LOC100227849 antibody, Sox9 antibody, sox9.L antibody
    Background
    SOX9 is a member of the family of SOX (Sry-type high mobility group box) genes that were first identified on the basis of region with high homology to that of Sry (Sex determining region Y). SOX9 is a transcription factor with a high mobility group DNA-binding domain that is expressed in all prechondrocytic and chondrocytic cells during embryonic development in a pattern that close parallels that of the gene for type II collagen. SOX9 is important in neural crest formation, and is involved in regulating subsequent epithelial-mesenchymal transition and migration. SOX9 recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal.Synonyms: CMD1, CMPD1, SRA1, SRY (sex determining region Y)-box 9, SRY-box 9, Transcription factor SOX-9
    Gene ID
    6662, 9606
    UniProt
    P48436
    Pathways
    EGFR Signaling Pathway, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
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