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Details for Product No. ABIN356911

Retina and Anterior Neural Fold Homeobox (RAX) (N-Term) antibody

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Antigen
Synonyms
AV120107, PRK, Pact, RAX, lear, dyt16, pact, prkra-a, prkra-b, rax, rbpa, Rx, RX, MCOP3, ey1, ey-1, 7530406A22Rik, E130303K03Rik, CG10052, DRx, Dmel\\CG10052, Drx, E97, PPH17, W60, bk50, drx, wom, RAX ... show more
Epitope
»Alternatives N-Term
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Application
»Alternatives ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
Pubmed 3 references available
Catalog no. ABIN356911
Quantity 0.4 mL
Price
346.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 6 to 8 Business Days
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human RAX.
Specificity This antibody detects Rax at N-term.
Purification Protein A column, followed by peptide affinity purification
Alternative Name RAX / RX
Background Rax plays a critical role in eye formation by regulating the initial specification of retinal cells and/or their subsequent proliferation. It binds to the photoreceptor conserved element-I (PCE-1/Ret 1) in the photoreceptor cell-specific arrestin promoter.
Alternate names: Retina and anterior neural fold homeobox protein, Retinal homeobox protein Rx
Molecular Weight 36805 Da
Gene ID 30062
NCBI Accession 9606
UniProt Q9Y2V3
Application Notes ELISA 1: 1,000. Western blot 1: 50 - 1: 100. Immunohistochemistry 1: 10 - 1: 50. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09% (w/v) sodium azide
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
Expiry Date 12 months
Background publications Mathers, Jamrich: "Regulation of eye formation by the Rx and pax6 homeobox genes." in: Cellular and molecular life sciences : CMLS, Vol. 57, Issue 2, pp. 186-94, 2000 (PubMed).

Mikkola, Bruun, Holm et al.: "Superactivation of Pax6-mediated transactivation from paired domain-binding sites by dna-independent recruitment of different homeodomain proteins." in: The Journal of biological chemistry, Vol. 276, Issue 6, pp. 4109-18, 2001 (PubMed).

Voronina, Kozhemyakina, OKernick et al.: "Mutations in the human RAX homeobox gene in a patient with anophthalmia and sclerocornea." in: Human molecular genetics, Vol. 13, Issue 3, pp. 315-22, 2004 (PubMed).

Alternatives for antigen "Retina and Anterior Neural Fold Homeobox (RAX)", type "Antibodies"
Hosts (17), (10)
Reactivities (24), (5), (3), (2), (2), (1), (1)
Applications (27), (12), (7), (3), (3)
Epitopes (8), (5), (4), (2), (2), (1)
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