FRAT1 antibody (Center)

Catalog No. ABIN356925

Product Details anti-FRAT1 Antibody

Target: FRAT1 (Frequently Rearranged in Advanced T-Cell Lymphomas (FRAT1))

Binding Specificity: Center

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FRAT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody detects FRAT1 at Center.

Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human FRAT1.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA 1: 1,000. Western blot 1: 50 - 1: 100. Immunohistochemistry 1: 10 - 1: 50´.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Target Details for FRAT1

Target: FRAT1 (Frequently Rearranged in Advanced T-Cell Lymphomas (FRAT1))

Alternative Name: FRAT1 (FRAT1 Products)

Synonyms: FRAT1 antibody, frat1 antibody, AW060382 antibody, gbp antibody, FRAT1, WNT signaling pathway regulator antibody, GSK-3 binding protein FRAT1 antibody, frequently rearranged in advanced T cell lymphomas antibody, frequently rearranged in advanced T-cell lymphomas antibody, frequently rearranged in advanced T-cell lymphomas 1 S homeolog antibody, FRAT1 antibody, frat1 antibody, Frat1 antibody, frat1.S antibody

Background: FRAT1 belongs to the GSK-3-binding protein family. It may function in tumor progression and in lymphomagenesis. It positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the association with GSK-3. It may play a role in tumor progression and collaborate with PIM1 and MYC in lymphomagenesis.Synonyms: FRAT-1, Frequently rearranged in advanced T-cell lymphomas, Proto-oncogene FRAT1

Molecular Weight: 29093 Da

Gene ID: 10023, 9606

UniProt: Q92837