ALDH6A1 antibody (N-Term)

Catalog No. ABIN356978

Product Details anti-ALDH6A1 Antibody

Target: ALDH6A1 (Aldehyde Dehydrogenase 6 Family, Member A1 (ALDH6A1))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALDH6A1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody detects ALDH6A1 at N-term.

Purification: Protein A column, followed by peptide affinity purification. The antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: KLH conjugated synthetic peptide selected from the N-terminal region of human ALDH6A1

Isotype: Ig Fraction

Application Details

Application Notes: ELISA 1: 1,000. Western blot 1: 50 - 1: 100. Immunohistochemistry 1: 10 - 1: 50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Target Details for ALDH6A1

Target: ALDH6A1 (Aldehyde Dehydrogenase 6 Family, Member A1 (ALDH6A1))

Alternative Name: ALDH6A1 / MMSDH (ALDH6A1 Products)

Synonyms: MMSADHA antibody, MMSDH antibody, Mmsdh antibody, cb850 antibody, wu:fb03a04 antibody, zgc:92082 antibody, 1110038I05Rik antibody, AI314632 antibody, aldehyde dehydrogenase 6 family member A1 antibody, aldehyde dehydrogenase 6 family, member A1 antibody, aldehyde dehydrogenase 6 family member A1 L homeolog antibody, methylmalonic acid semialdehyde dehydrogenase antibody, methylmalonate-semialdehyde dehydrogenase (CoA acylating) antibody, aldehyde dehydrogenase family 6, subfamily A1 antibody, ALDH6A1 antibody, Aldh6a1 antibody, aldh6a1.L antibody, CCNA_02357 antibody, aldh6a1 antibody, VAA_RS07845 antibody

Background: ALDH6A1 belongs to the aldehyde dehydrogenases family of proteins. This enzyme plays a role in the valine and pyrimidine catabolic pathways. This protein is a mitochondrial methylmalonate semialdehyde dehydrogenase, and catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids.Synonyms: Aldehyde dehydrogenase family 6 member A1, Malonate-semialdehyde dehydrogenase [acylating], Methylmalonate-semialdehyde dehydrogenase [acylating] mitochondrial

Molecular Weight: 57858 Da

Gene ID: 4329, 9606

UniProt: Q02252

Pathways: Brown Fat Cell Differentiation